Phenylketonuria (PKU) is an inheritable disorder whereby phenylalanine accumulates in the blood. If left untreated, the disorder can lead to severe health problems and intellectual disabilities. If individuals II-2 and II-8 had a child, what is the percent probability of them having children with PKU? Answer % Record your answer rounded to one decimal place.

what is the probability that a couple (both heterozygous for the same recessive mutation) will have two children with the disease if the couple plans to have four children in total?

The percentage chance that the mother described above will give birth to a daughter with mid-digital hair and freckles is what percentage?

Neural Tube Defects (NTDs) are one of the most severe congenital malformations. A study was conducted to determine whether supplementation with folic acid or a mixture of seven other vitamins (A, D, B1, B2, B6, C, and nicotinamide) around the time of conception could prevent neural tube defects. A total of 1817 women at high risk of having a pregnancy with a neural tube defect (because of a previous affected pregnancy) were allocated at random to one of four groups: 1) folic acid; 2) other vitamins; 3) both; 4) neither. 1195 had a completed pregnancy; 27 of these had a known neural tube defect, 6 in the folic acid groups and 21 in the two other groups.  This resulted in a risk ratio= 0.28. Based on the results of the study, which of the following is an appropriate conclusion? a)There is no difference in the effect of folic acid on NTDs b) None of these c) Folic acid increases risk of NTDs d) Folic acid is protective against NTDs