Use the following information to answer the next five questions. During the summer of 2013 it was determined that a small Nigerian village had a population of 2,089 people. The per capita incidence of people born with sickle- cell anemia (an autosomal recessive disease) in this village, was the highest in the country with 324 people in this population having the condition. The people with sickle-cell anemia require extensive therapy for this otherwise lethal disease. However, a heterozygous advantage exists with carriers of the sickle-cell allele providing resistance to malaria, a lethal disease that is highly prevalent in this village. People heterozygous for the sickle cell allele produce an environment in some of their blood cells that is toxic to the parasite that causes malaria. Show ALL calculations 1. Calculate the phenotypic frequency of sickle- cell anemia in this population expressed as a number between 0 and 1 and rounded to 2 decimal places 2. Calculate the frequency of the recessive allele in this population expressed as a number between 0 and 1 and rounded to 2 decimal places. 3. Calculate the frequency of the dominant allele in this population expressed as a number between 0 and 1 and rounded to 2 decimal places. 4. How many people (to the nearest whole person) are expected to be resistant to malaria but NOT have full sickle cell anemia 5. Of all the people who do NOT suffer from sickle- cell anemia, how many (to the nearest whole person) are expected to be genotypically homozygous?

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Match the genetic disorder to the descriptions below: Edward Syndrome Jacob Syndrome Patau Syndrome Turner Syndrome Prader-Willi Syndrome Down Syndrome (trisomy) Klinefelter Syndrome Cri du Chat 18-Q Deletion Syndrome Translocation Down Syndrome   ________      deletion of part of the P arm of chromosome 5.  Improperly developed                         larynx causes cat-like cry until age 2.  IQ is under 20. ________      deletion of Q arm of chromosome 15.  Affected individuals have a small                         head, are retarded, and exhibit bizarre behavior.   ________      deletion of Q arm of chromosome 18.  Affected individuals have thirteen                         pairs of ribs (normal is 12 pairs) and IQ under 30. ________      extra 21st chromosome attaches to chromosome 14.  Affected individ-                         uals exhibit epicanthic folds of eyelids, simian crease in palms, and                         retardation. ________      trisomy 18.  Affected individuals…