Oxidation of NADH and FADH2 in the electron transport system are similar in that: (READ THESE ANSWER CHOICES CAREFULLY!)   a Both give their electrons to Complex I.   b Both give their electrons directly to Ubiquinone (CoQ).   c Both require Ubiquinone, Complex III, Cytochrome C, and Complex IV, ultimately resulting in reduction of O2   d Both result in pumping of H+ from the intermembrane space to the mitochondrial matrix.

Which of the following components of the mitochondrial electron transport chain is not integral to the inner mitochondrial membrane (of a typical eukaryotic cell)? A. the cytochrome c oxidase complex B. coenzyme Q (ubiquinone) C. the cytochrome b-cı complex D. cytochrome c E. the cytochrome a-a3 complex

Which complex of the mitochondrial electron transport chain accepts electrons directly from NADH (the reduced form of nicotinamide adenine dinucleotide)? NADH dehydrogenase (complex I) FADH2 dehydrogenase (complex II) cytochrome b-c1 (complex III) cytochrome c oxidase (complex IV) the ATP synthase complex

In oxidative phosphorylation (mark all that are true)... Choice 1 of 7:Succinate contributes 2e- to Complex II and 2H+ to the mitochondrial proton gradient. Choice 2 of 7:NADH in the matrix passes 2 e- to coenzyme Q via Complex I. Choice 3 of 7:Complexes I, II, III, and IV each contribute to the matrix proton gradient. Choice 4 of 7:O2 stabilizes the catalytically active conformation of Complex V. Choice 5 of 7:Reversible protonation of c subunits leads to rotation of the Complex V gamma subunit. Choice 6 of 7:Each β subunit can bind ATP tightly under the right conditions. Choice 7 of 7:For every 3 protons that pass across the inner mitochondrial membrane, 1 ATP is produced.   Below are screenshots of the answer from two different sources (for your consideration)

Which complex of the mitochondrial electron transport chain accepts electrons directly from NADH (the reduced form of nicotinamide adenine dinucleotide)? NADH dehydrogenase (complex I) FADH2 dehydrogenase (complex II) cytochrome b-c1 (complex III) cytochrome c oxidase (complex IV) the ATP synthase complex

Rotenone is an insecticide that is not toxic to plants, but is highly toxic to fish and insects. (it will also kill mammals, but it doesn’t easily get into our cells). When Rotenone is added to cells in vitro, ATP production stops, oxygen is no longer reduced and NADH builds up. Based on these results, explain what is a possible mechanism of action for Rotenone?

Which complex of the mitochondrial electron transport chain accepts electrons directly from NADH (the reduced form of nicotinamide adenine dinucleotide)?  NADH dehydrogenase (complex I) FADH2 dehydrogenase (complex II) cytochrome b-c1 (complex III) cytochrome c oxidase (complex IV) the ATP synthase complex Chapter 14, Pg. 78

Concerning the citric acid cycle (TCA cycle), which of the following statements is false? a. Substrate level phosphorylation in the TCA cycle produces 2 GTP per the oxidation of a single glucose molecule b. The TCA cycle generates electron carriers c. Oxidation of pyruvate in the matrix of the mitochondria produces sixteen total electrons  d. The fate of the carbonyl carbon of acetyl CoAin the TCA cycle is to be lost as CO2 in the second turn e. Radiolabeling of the methyl carbon of pyruvate in the TCA cycle shows the carbon signal to split through successive turns

Calculate the ATP yield for the complete oxidation of the ketone body 3-hydroxybutryate to 4 CO2 in the mitochondrial matrix. Use P:O ratios of 2.5 for NADH and 1.5 for QH2. Draw the chemical reaction and the movement of electrons (including the enolate intermediate) necessary for the spontaneous decarboxylation of acetoacetate to acetone and CO2. (Hint: review the mechanism of step 4 in glycolysis and step 3 in the citric acid cycle). Why is acetoacetate undergoing spontaneous decarboxylation while 3-hydroxybutyrate does not?

Citrate synthase is a nuclear-encoded enzyme of the Citric Acid Cycle.  The enzyme is functional in the mitochondrial matrix.    Looking at the system required for mitochondrial targeting and import of citrate synthase, which of the following statements are correct?     1.  Proper import and processing of citrate synthase is dependent upon other proteins found in the mitochondria. 2.  Because of the signal peptide, the mature functional enzyme is actually longer than it would be if it was coded by the organelle genome. 3.  Because the citrate synthase signal peptide doesn’t have a precise amino acid signature, mutations that slightly change the primary sequence have no effect on targeting. 4.  To get citrate synthase into the mitochondrial matrix requires two signal sequences: one to get it across the outer membrane and a second to get it across the inner membrane.   A.  1,2 and 3   B.  1 and 3   C.  2 and 4   D.  4 only   E. All of 1,2,3 and 4 are correct