Q: At which level of gene regulation shown in Figure 16.1 does attenuation occur?
A: Attenuation is a process which involves a presence of a stop signal which suggests premature…
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A: Answer: Introduction: Mutation- These are the random heritable changes that occurs in the DNA…
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Q: Mutant C has had the first 5 base pairs deleted (position 1-5). Does this mutation change the…
A: Translation is the process which is responsible for synthesis of protein from the mRNA.
Q: WILD-TYPE MC1R GENE (LIGHT COAT-COLOR PHENOTYPE) DNA GTG TAC GAA CGT mRNA Amino Acid
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Q: What is the sequence of the first 10 nucleotides of the transcript of this gene? 5' 3'
A: Transcription is mainly the process of making RNA from gene sequence and transcript is the product…
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Q: How does histone acetylation alter chromatin structure? (300 word limit)
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Q: 6. This is where the RNA polymerase is bound and a short region of DNA is accessible to begin the…
A: In bacteria,The RNA poltmerase enzyme binds and unwinds promoter DNA and open promoter complex form…
Q: This question is regarding the 6 areas that can be involved in the control of gen expression: Part 1…
A: Gene expression is the transcription of a gene into mRNA and its subsequent translation into…
Q: The gel below is the result of a Sanger sequencing run of part of Exon 3 of the Mstn gene, which…
A: In Sanger sequencing, the objective is to analyze the sequence of a given strand of DNA. To obtain…
Q: statement is true. Both statements are false. 1. Epigenetics does not consider how exposure to…
A: Epigenetics is the study of how your behaviour and environment can influence how your genes…
Q: Euchromatin is said to be transcriptionally-active while Heterochromatin is said to be…
A: Euchromatin exists in decondensed form and is found in the distal arms of the chromosome. It is…
Q: Select all the possible mutation types for the following observed phenotype resulting from a…
A: Need to find which of the following mutation is happened in protein to express in wrong cell
Q: 1. DNA Sequence: TẠC TCC GGC TCT CCC AGT TGA ACT Mutated Sequence: TAC TCG GCT CTC CCA GTT GAA CT…
A: As per our guidelines, we are supposed to answer only one question. Please repost other question in…
Q: An hnRNA molecule contains three exons, with the middle one being an “alternative” exon. How many…
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A: The chromosomal theory of inheritance provides the idea that genes are located on the chromosomes.…
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A: Cell is the basic structural, functional and biological unit of all organisms.Cell is the smallest…
Q: WILD-TYPE MC1R GENE (LIGHT COAT-COLOR PHENOTYPE DNA TTG AGG TGG GCG TGT CCG CAA GGA…
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Q: Describe the 4 types of suppressor high copy suppression, bypass suppression, nonsense suppression,…
A: Since we only answer 1 question in case of multiple question, we’ll answer the first question as the…
Q: (select all correct answers) Each transposon must have Select one or more: O a. two inverted repeats…
A: A transposable element (TE, transposon, or jumping gene) is a DNA sequence that can move around…
Q: Shown below is the 5' end of an mRNA molecule. What are the first three (N-terminal) amino acids of…
A: Through transcription the DNA molecule is converted into mRNA.
Q: The FOXP2 gene is sometimes called the “language gene.” Why is this name inaccurate?
A: The FOXP2 gene present in many vertebrate including human beings. It encodes a protein Forkhead…
Q: Which partial peptide sequence is most likely to be part of a B-turn? O DERKY O LASIK O C VPGE O…
A: Proteins are the polymers of amino acids that of an alpha carbon or chiral carbon having four…
Q: Proteins A,B,C, and D in the diagram are encoded by different genes and interact with each other.…
A: Answer. There are many different types of mutations that can occur in a coding sequence that can…
Q: three different types of loss of function mutations and in each case explain how the mutation exerts…
A: A mutation is any alteration of the base sequence of the DNA or RNA. Since mutation alters the base…
Q: 1 4 6 7 8. 9. Transcriptional stop sequence ТАTA box ATG TAA AUG UAA Here is a diagram of a human…
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Q: You are studying a mutation in mice, which acts dominantly. Mice that have only one copy of the…
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Q: What is a transcriptome, a genome and a proteome. How do they differ and why is the term proteome…
A: Definition: - A transcriptome is defined as the full range of mRNAs expressed by an organism. A…
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A:
Q: After an MRNA primary transcript is created, a modified guanine nucleoside triphosphate is added to…
A: The genetic information in a cell is processed in a series of steps namely replication,…
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Q: Due to a nucleotide substitution, the fourth residue of H3 in a specific tissue cell of an organism…
A: Protein domains are the structural units of protein that are responsible for specific function of…
Q: A full-length eukaryotic gene is inserted into a bacterial chromosome. The gene contains a complete…
A: Transcription in eukaryotes occurs in three consequent stages that start with the initiation step,…
Q: There are several different types of genes within a genome that serve specific functions within the…
A: A genome is an organism's full set of genetic information. It contains all of the information that…
Q: A full-length eukaryotic gene is inserted into a bacterial chromosome. The gene contains a complete…
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Q: You are studying celiacs disease and have identified a potential gene for the disease using linkage…
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Q: The mass of a gene is 32,400 units. The amount of introns is twice the amount of exons. What is the…
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Q: Please put the following steps of eukaryotic protein synthesis in order from first (1) to last (4)…
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A: The term forward genetics is associated with a method that is utilized for studying the genetics…
Q: does P53 It integrate together information from over a hundred proteins about the mutational state…
A: A gene that makes a protein that is found inside the nucleus of cells and plays a key role in…
Q: 5'-AGA-ACT-AAA-CTA-TCG-CTT-CGT--3' mRNA: original protein
A: The flow of genetic information from DNA to RNA, RNA to protein synthesis is called central dogma.…
Q: We looked at RNA-mediated mechanisms of gene regulation in both eukaryotes and prokaryotes. a.…
A: All eukaryotic prokaryotes are homologous to one another and to prokartoyotic RNA polymerase. in…
Q: 1. Where would the RNA polymerase II bind this piece of DNA = region B 2. What DNA sequence would…
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Q: ome genes have the genetic code responsible for coding more than one protein based on the process of…
A: Alternative splicing is the process by which a single gene can give rise to multiple messenger RNA…
Q: Select from the options below the different types of mutations . Please select all that apply. -gene…
A:
Q: As the most junior member of a lab, you are tasked with generating cell lines that accumulate DNA…
A: If DNA damage occurs then the cell cycle will be arrested and the cell try to repair the damaged…
- Most disease associated
genetic variants exist outside of gene coding regions, how are these thought to promote disease development? (300 word limit)
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- Describe the 4 types of suppressor high copy suppression, bypass suppression, nonsense suppression, protein interaction . in your Own words. Often geneticists look for suppressors to find interactive proteins. Which of the type(s) of suppressors you put for part a will help to identify interacting proteins, and which type(s) will not? What are two (or one, if we don’t get a chance to talk about two of them in class) other techniques (not necessarily “genetic” techniques, but at least, lab techniques) that help to identify identifying proteins?Explain how the same gen can be highly expressed in several distinct tissues (e.g. brain, liver, and lung) of an organism, yet silent in all other tissues. Hint: The answer is not that they share the same tissue-specific transcription factors..Give 4 examples of transcription factors / non-structural proteins you have learned in this course? Identify the most commonly used technique for diagnosing COVID-19? And the clinical sample for each technique. …….…… virus can cause encephalitis, cancer, sexually transmitted disease, infect external genitalia, mucosal surfaces, gladiatorum, and/or other diseases. How can the infection with this virus be avoided? Suggest two ways of prevention or to destroy the virus.
- A cell has a mutated mediator protein. a) How will this affect transcription of genes? (circle an answer below) No transcription Weak transcription will occur Strong transcription will occur b) Why? Describe your choice aboveMost nonsense mutations in a structural gene (coding for a protein) have a null phenotype. How many different single base substitution mutations in a protein coding sequence can produce a nonsense mutation? 7 Fr ♥ T: - - A - BIE E % $The RB (retinoblastoma) protein normally [ Select] ["keep a transcription factor in an inactive state", "keep a transcription factor in an active state", "keep the CDK in a phosphorylated state", "block the function of the APC"] ...But it can be deactivated by [ Select ] ["ubiquitination", "methylation", "phosphorylation", "the use of a GAP"] .Mutations in Rb can lead to cancer because these mutations [ Select ] ["result in constitutive transcription leading to promotion of the cell cycle", "keep CDKs off", "deactivate p53", "increase the production of growth hormones"] PLEASE SELCET THE CORRECT ONE FOR SECTION ONE . EACH SENTECNE HAVE 4 SECTION TO PICK FROM.
- What is the rationale for synthesizing and rapidly degrading p53 protein in the cell?5 5 S 6 5 5 5 6 U 6 U 6 5:14 PM | 0.2KB/s HHHHH R R U RUUR ARU AP AP R U U R R AP R R R AP MOLECULAR...GENETICS. Describe gene regulation at transcription level. Explain the role of antsense RNA in control mechanism. Describe translational control mechanisms. Describe common DNA damages. Distinguish excision and mismatch repair. Describe the role of recA protein in recombination repair Elaborate on SOS repair mechanism. Define thymine dimer. How are they formed and repaired? Describe the molecular basis of mutation. 11 Leu+ Met+ Arg+ Write a detailed note on spontaneous mutation. Explain about mutant detection methods. Define reverse mutation. Describe the mechanism underlying Intragenic and intergenic suppressor mutations Describe the transposition mechanisms. 13 Vo LTE UNIT IV Time (Min) Describe the process of generalised transformation occurring in bacterial chromosome and plasmid. Elaborate on molecular mechanism and significance of transformation 22 Describe the process of…What is the function of RAG1? What will happen if RAG1's function is lost due to mutations?
- BRCA1 is mutated in a large percentage of hereditary breast and ovarian cancers. BRCA1 protein serves as a key enzyme in repairing DNA double-strand breaks. More than 800 mutations in the BRCA1 are clinically significant. This collection of mutations include missense mutations, small deletions, and large rearrangements that result in a protein with reduced function or no protein product. BRCA1 functions by interacting with a variety of proteins, such as Rb, Myc, cyclin-dependent kinase (CDK), and Rad50/51. Rb is important for cell cycle arrest; Myc is a transcription factor that activates genes required for cell proliferation; activated CDK promotes cell cycle progression; and Rad50/51 proteins facilitate repair of DNA double-strand breaks. How many of the mutations listed below would lead to excessive cell growth when the cell was either homozygous or heterozygous for the mutation? Increased expression of Myc Constitutively active Rad50/51 A null mutation in Rb Continuous production…1). In the absence of this enzyme, a substance called ceroid lipofuscin accumulates in lysosomes in the brain, resulting in seizures, blindness, decline in cognitive function and motor skills, dementia, and death by the late teens or early 20’s. The TPP1 gene is 6695 bp in length. Think about the characteristics of Batten disease, and then suggest an approach to gene therapy that might be effective for this specific genetic disorder. You may assume that your research team is working in the U.S. and your research is funded by a grant from the National Institutes of Health (NIH). Please EXCLUDE the use of CRISPR from consideration. A. Will you use germline or somatic cell gene therapy? Please NAME and DEFINE the form of gene therapy selected, then explain WHY this is the most appropriate choice.1). In the absence of this enzyme, a substance called ceroid lipofuscin accumulates in lysosomes in the brain, resulting in seizures, blindness, decline in cognitive function and motor skills, dementia, and death by the late teens or early 20’s. The TPP1 gene is 6695 bp in length. Think about the characteristics of Batten disease, and then suggest an approach to gene therapy that might be effective for this specific genetic disorder. You may assume that your research team is working in the U.S. and your research is funded by a grant from the National Institutes of Health (NIH). a) Hypothetically, what specific type of VECTOR will you use to perform your gene therapy? Please select from the following list of potential vectors: disabled retrovirus, adenovirus, adeno-associated virus (AAV), or herpes simplex virus (HSV), then give two reasons why this specific vector is the most appropriate for your gene therapy. Please explain why you were able to rule out the other potential…
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