Many common materials that we ingest, though quite safe in reasonable quantities, become toxic when taken in very large doses. A measure of toxicity is the LD50 value (Lethal Dose, 50%). It is the quantity of material, expressed in mg of material per kg of subject-body-weight that, if administered to a population of subjects, would cause 50% of the population to die. The LD50 value for FD&C Red Dye No. 40 is >10,000 mg/kg in rats. Assume that the LD50 value for humans is the same as for rats. Calculate the number of mg of Allura Red present in an 9 fluid ounce glass of the beverage you used in this lab and use this calculation to determine the number of such glasses of Allura Red sports drink required to reach the LD50 of 10,000 mg of Allura Red/kg body weight. Assume that the concentration of Allura Red in the beverage is 0.000038 M and the person has a body weight of 175 lbs. The molar mass of Allura Red is 496.42 grams/mol 1 fl oz = 29.5735 mL 2.205 lbs = 1 kg You may assume two significant figures but do not use scientific notation. Do not include units with your answer.
Many common materials that we ingest, though quite safe in reasonable quantities, become toxic when taken in very large doses. A measure of toxicity is the LD50 value (Lethal Dose, 50%). It is the quantity of material, expressed in mg of material per kg of subject-body-weight that, if administered to a population of subjects, would cause 50% of the population to die. The LD50 value for FD&C Red Dye No. 40 is >10,000 mg/kg in rats. Assume that the LD50 value for humans is the same as for rats.
Calculate the number of mg of Allura Red present in an 9 fluid ounce glass of the beverage you used in this lab and use this calculation to determine the number of such glasses of Allura Red sports drink required to reach the LD50 of 10,000 mg of Allura Red/kg body weight. Assume that the concentration of Allura Red in the beverage is 0.000038 M and the person has a body weight of 175 lbs.
The molar mass of Allura Red is 496.42 grams/mol
1 fl oz = 29.5735 mL
2.205 lbs = 1 kg
You may assume two significant figures but do not use scientific notation.
Do not include units with your answer.
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