In a certain population of African people, 9% of the population is born with sickle cell anemia. This is a recessive disease. What % of the population is: Homozygous Dominant? Heterozygous?
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- Heterozygote advantage is an interesting condition in those individuals who have one of each allele (dominant and recessive) have a higher survival rate than those individuals who are either homozygous dominant or homozygous recessive. Sickle-cell anemia is such a genetic disease associated with the recessive allele. Normal homozygous individuals (SS) have normal blood cells that are easily infected with the malarial parasite. Thus, many of these individuals become very ill from the parasite and many die. Individuals homozygous for the sickle-cell trait (ss) have red blood cells that readily collapse when deoxygenated. Although malaria cannot grow in these red blood cells, individuals often die because of the genetic defect. However, individuals with the heterozygous condition (Ss) have some sickling of red blood cells, but generally not enough to cause mortality. In addition, malaria cannot survive well within these "partially defective" red blood cells. Thus, heterozygotes tend to…In a hypothetical population, 16% have sickle-cell anemia. The population is in Hardy-Weinberg equilibrium. ( sickle-cell anemia is recessive) What percentage of the population produces only normal hemoglobin? What percentage of the population is heterozygous?Cystic fibrosis is an autosomal recessive disorder that affects 1 in 3 000 newborns with Caucasian background. It causes thick mucus build up in various organs and can cause damages and problems in respiratory and digestive systems. a) What is the frequency of the cystic fibrosis allele in the Caucasian population? Show all your work and express your answer as a value between 0 and 1 rounded to two decimal places. b) What percentage of the Caucasian population would be carriers for cystic fibrosis? Show all your work and express your answer rounded to two decimal places. c)If two individuals are carriers of the cystic fibrosis allele, what is the probability that they would have a girl without cystic fibrosis? Show all your work (including the Punnett square) and express your answer as a value between 0 and 1 rounded to two decimal places.
- Sickle cell anemia is a blood disorder that is expressed with incomplete dominance. The homozygous recessive phenotype has sickle shaped red blood cells that cause anemia and often death if untreated. If an unaffected father and mother move to the United States from Sub-Saharan Africa and several of their offspring have sickle cell anemia, what do we know about both parents' genotypes? One is homozygous recessive, the other is heterozygous They are both heterozygous They are both homozygous recessive One is homozygous dominant, the other is heterozygousHumans who are born homozygous for the recessive sickle cell allele die of sickle cell anemia, while those who are heterozygous are resistant to malaria. 5% of the population of the Congo are homozygous recessive for the sickle cell allele. What percentage of the population is resistant to malaria?As seen in the photo, Labradors come in three colors-- black, brown and yellow. What is the genetic basis for these different coat colors? One gene produces melanin, a pigment which is deposited in the dog's fur and makes the color dark. With this gene, allele B (black) is dominant to allele b. Only in the case of a recessive homozygote (bb) will the dog's phenotype be brown. The regulatory gene is separate from the melanin gene but it acts as a switch, either turning the melanin gene on or turning it off. Allele E is dominant and allows for the melanin to be deposited in the dog's fur ("on" switch), but if the switch gene is a recessive homozygote, the melanin is blocked ("off" switch) and a yellow dog is the result! 1. Two other Labradors mate and produce puppies. Their genotypes are Bbee and BbEe. What color are each parent and what are the phenotypic rations of their offspring in the F1 Generation? Show your work with a Punnett square.
- As seen in the photo, Labradors come in three colors-- black, brown and yellow. What is the genetic basis for these different coat colors? One gene produces melanin, a pigment which is deposited in the dog's fur and makes the color dark. With this gene, allele B (black) is dominant to allele b. Only in the case of a recessive homozygote (bb) will the dog's phenotype be brown. The regulatory gene is separate from the melanin gene but it acts as a switch, either turning the melanin gene on or turning it off. Allele E is dominant and allows for the melanin to be deposited in the dog's fur ("on" switch), but if the switch gene is a recessive homozygote, the melanin is blocked ("off" switch) and a yellow dog is the result! Review the information on Labrador retrievers above. What are the phenotypic ratios of the F1 generation offspring of two dihybrids? Make sure to match the numbers with coat colors (e.g, which number in the ration goes with which color). Use a Punnett square to…The fur color gene in rabbits has a dominant allele B with a black phenotype and a recessive allele with a brown phenotype. The rabbit hair length gene has a dominant allele S for short hair, and a long hair recessive allele s. In a cross between a homozygous black-long-hair rabbit with a homozygous brown-short rabbit, what would be the genotype(s) B_s_ v and phenotype(s) [ Select ] of the F1 generation? What would be the genotype(s) [ Select ] and phenotype(s) [ Select ] of the F2 generation?The ABO blood group in humans is controlled by a single locus with three different alleles. Homozygosity for IA produces type A blood. Homozygosity for IB produces type B blood. Homozygosity for IO produces type O blood. Type AB blood is produced by the genotype IA/IB. IO is recessive to IA and IB; thus, IA/IO gives type A blood and IB/IO gives type B blood. In the United States, the allele frequencies for the ABO alleles are given below. The Rh factor in blood typing also has multiple alleles, but the alleles can be classified into two types, positive and negative. Rh+ is dominant over Rh−. The allele frequencies of these alleles are also indicated below. The MN blood antigen trait is controlled by two codominant alleles at a single locus. Type M individuals are homozygous for the M allele, type MN individuals are heterozygous, and type N individuals are homozygous for the N allele (codominant). In the United States, the allele frequencies for this blood group are also indicated…
- The allele of the gene responsible for the lung disorder, cystic fibrosis rose to prominence in Europe in the 1800s. Cystic fibrosis disease results from thick mucus accumulating in the lungs, which occurs in individuals who are homozygous for the CF allele. A pleiotropic effect is that heterozygous individuals are less likely to suffer from diarrhea. During the European cholera epidemics of the 1800s, resistance against diarrhea conferred a survival advantage such that approximately one in every 400 people in some European populations have cystic fibrosis. Fill in the table below with the genotype and allele frequencies for this 1 in 400 occurrence and provide the Hardy-Weinberg principle model you will be using. (Assume that individuals with the cystic fibrosis trait (CF) reproduce normally and that good sanitation means that there is currently no fitness advantage to diarrhea resistance.) phenotype CF DR normal (totals) Genotype cc Cc CC Number of Individuals 1 ______…Tay-Sachs is a recessive lethal disease in which there is neurological deterioration early in life. This disease is rare in the population overall but is found at relatively high frequency in Ashkenazi Jews from Eastern Europe. A woman has a maternal uncle who had the disease. Her father does not come from a high-risk population. Her husband’s sister died of the disease at an early age. Draw the pedigree of the individuals described. Include the genotypes where possible.In humans, Cystic Fibrosis an autosomal recessive trait, currently with medicine advances people affected by this disease can live until the 40s and 50s even. A couple in which the mother is a known carrier for this disease plans to have 4 children with a man who is not affected either but had his father who had the disease. A) Please state the genotypes of the parents. Use C to denote the dominant allele and c as the recessive B) Determine the probability that the first 2 children born have Cystic Fibrosis and the 2 last children are not affected. C) In general, what proportion of the children are expected to be female carriers of Cystic Fibrosis trait?