How do activators facilitate transcription? Activator (inactive) Activator- binding site RNA polymerase Promoter Transcription normally off. RNA polymerase cannot bind to the promoter unless the activator is bound to the activator-binding site, but the activator is in an inactive form. Inducer Activator (active) Inducer helps turn transcription on. NNNNA Transcription Inducer binds to the activator and changes its shape, allowing the activator to bind to the site. RNA polymerase can then bind to the promoter and initiate transcription.

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter29: Transcription And The Regulation Of Gene Expression
Section: Chapter Questions
Problem 3P: Substrate Binding by RNA Polymerase RNA polymerase has t binding sites for ribonucleoside...
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How do activators facilitate transcription?
Activator
(inactive)
Activator-
binding site
RNA
polymerase
Promoter
Transcription
normally off.
RNA polymerase cannot bind to the promoter unless the activator
is bound to the activator-binding site, but the activator is in an
inactive form.
Inducer
Activator
(active)
Inducer helps turn
transcription on.
Transcription
Inducer binds to the activator and changes its shape, allowing the
activator to bind to the site. RNA polymerase can then bind to the
promoter and initiate transcription.
Transcribed Image Text:How do activators facilitate transcription? Activator (inactive) Activator- binding site RNA polymerase Promoter Transcription normally off. RNA polymerase cannot bind to the promoter unless the activator is bound to the activator-binding site, but the activator is in an inactive form. Inducer Activator (active) Inducer helps turn transcription on. Transcription Inducer binds to the activator and changes its shape, allowing the activator to bind to the site. RNA polymerase can then bind to the promoter and initiate transcription.
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