Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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**Understanding Zebrafish Addiction to Substances**

*How can the zebrafish become addicted to the same substances that humans often abuse, such as narcotics?*

1. **Lateral Line System Stimulation:**
   - The lateral line system in zebrafish is electrically stimulated by the presence of dissolved narcotics, causing them to swim towards the water with the highest concentration.

2. **Nutritional Ingestion:**
   - As herbivores, zebrafish are able to obtain nutrition by ingesting cannabinoids.

3. **Homologous Neural Receptors:**
   - The central nervous system of humans and zebrafish have homologous neural receptors, neurotransmitters, and signaling pathways.

4. **Positive Conditioning:**
   - Zebrafish seek drugs in response to positive conditioning; they are trained to associate drugs with food rewards.

5. **Central Nervous System Limitation:**
   - Zebrafish do not have a central nervous system elaborate enough to become addicted to psychoactive substances.

**Note:** Understanding the mechanisms of addiction in zebrafish can provide important insights into human addiction and aid in developing effective treatments.
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Transcribed Image Text:**Understanding Zebrafish Addiction to Substances** *How can the zebrafish become addicted to the same substances that humans often abuse, such as narcotics?* 1. **Lateral Line System Stimulation:** - The lateral line system in zebrafish is electrically stimulated by the presence of dissolved narcotics, causing them to swim towards the water with the highest concentration. 2. **Nutritional Ingestion:** - As herbivores, zebrafish are able to obtain nutrition by ingesting cannabinoids. 3. **Homologous Neural Receptors:** - The central nervous system of humans and zebrafish have homologous neural receptors, neurotransmitters, and signaling pathways. 4. **Positive Conditioning:** - Zebrafish seek drugs in response to positive conditioning; they are trained to associate drugs with food rewards. 5. **Central Nervous System Limitation:** - Zebrafish do not have a central nervous system elaborate enough to become addicted to psychoactive substances. **Note:** Understanding the mechanisms of addiction in zebrafish can provide important insights into human addiction and aid in developing effective treatments.
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