have generated 5 different cancer cell lines in your laboratory. In cancer cell line A there is a deletion of gene A In cancer cell line B, the promoter for gene B is over-methylated In cancer cell line C, there is a nonsense mutation near the start codon of gene C In cancer cell line D, there is a duplication of gene D In cancer cell line E, a translocation puts gene E close to an active promoter Each of the genes above
Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
You have generated 5 different cancer cell lines in your laboratory.
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- In cancer cell line A there is a deletion of gene A
- In cancer cell line B, the promoter for gene B is over-methylated
- In cancer cell line C, there is a nonsense mutation near the start codon of gene C
- In cancer cell line D, there is a duplication of gene D
- In cancer cell line E, a translocation puts gene E close to an active promoter
Each of the genes above is implicated in cancer. What is most likely, given the information?
- Gene A is likely to be a: Proto-oncogene/ Tumor Suppressor/ Neither
- Gene B is likely to be a: Proto-oncogene/ Tumor Suppressor/ Neither
- Gene C is likely to be a: Proto-oncogene/ Tumor Suppressor/ Neither
- Gene D is likely to be a: Proto-oncogene/ Tumor Suppressor/ Neither
- Gene E is likely to be a: Proto-oncogene/ Tumor Suppressor/ Neither
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