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Fill in ALL the charts AND answer every question/fill in the blank. Make sure it is ALL accurate and complete.

Fill in ALL the charts AND answer every question/fill in the blank. Make sure it is ALL accurate and complete.

Human Heredity: Principles and Issues (MindTap Course List)
Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter4: Pedigree Analysis In Human Genetics
Section: Chapter Questions
Problem 17QP: Analysis of X-Linked Dominant and Recessive Traits A young boy is color-blind. His one brother and...
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Fill in ALL the charts AND answer every question/fill in the blank. Make sure it is ALL accurate and complete.
Autosomal Dominant Disorder: Huntington's Disease 1. Huntington's disease is a neurological disease affecting humans. It has a late-onset and symptoms include involuntary muscle movements due to degeneration of the nervous system. Huntington's Disease is an autosomal dominant genetic disorder. A woman with the phenotype of Huntington's disease and the genotype Hh has children with a man with a normal (no Huntington's Disease) phenotype and the genotype hh. What are the chances that a particular child will have Huntington's Disease? a. Phenotypes of the parents: Mother: b. Genotypes of the parents: c. Gamete genotype(s): d. Punnett Square: (egg) Mother: Egg: (sperm) Father: Father: Sperm : e. List all possible genotypes of offspring of these parents: a. Which of these genotypes are heterozygous? b. Which of these genotypes are homozygous? f. List all the possible phenotypes of offspring of these parents: g. Calculate the probability of each genotype and phenotype as listed. Fill in table below on the following page.
Transcribed Image Text:Autosomal Dominant Disorder: Huntington's Disease 1. Huntington's disease is a neurological disease affecting humans. It has a late-onset and symptoms include involuntary muscle movements due to degeneration of the nervous system. Huntington's Disease is an autosomal dominant genetic disorder. A woman with the phenotype of Huntington's disease and the genotype Hh has children with a man with a normal (no Huntington's Disease) phenotype and the genotype hh. What are the chances that a particular child will have Huntington's Disease? a. Phenotypes of the parents: Mother: b. Genotypes of the parents: c. Gamete genotype(s): d. Punnett Square: (egg) Mother: Egg: (sperm) Father: Father: Sperm : e. List all possible genotypes of offspring of these parents: a. Which of these genotypes are heterozygous? b. Which of these genotypes are homozygous? f. List all the possible phenotypes of offspring of these parents: g. Calculate the probability of each genotype and phenotype as listed. Fill in table below on the following page.
Table 1: Expected Probabilities for Huntington'sDisease Genotype Genotype Phenotype Genotype probability as a percent HH Hh hh probability as a fraction Table 2. Data for Huntington's Disease Genotype Total # (Total # HH Hh h. What are the chances a child will have Huntington's Disease? Report data as a percentage: as a fraction: We are going to test the ratio of offspring given the parental genotypes above for Huntington's Disease by using a coin toss. The procedure is: 1. Obtain two coins. One represents the possible genotype(s) of the egg. The other represents the possible genotype(s) of the sperm. 2. Get one coin that represents the gametes of the mother. Each side of the coin represents one allele in a single gamete. Repeat for the father. 3. One student represents the mother and will flip the mother's coin. A second student represents the father and will flip the father's coin at the SAME time. 4. Note the two gametes that are face up. This represents the genotype of the offspring. Tally this genotype in the table below. 5. Repeat steps 1-4 24 times. hh Phenotype probability as a fraction genotype after 24 tosses genotype /24) X 100 in % Phenotype probability as a percent Probability Phenotype Total # from phenotype after 24 Punnett Square in % tosses (total # phenotype /24) x 100 in % Probability from Punnett Square in % Did your results from the coin tosses support your prediction from the Punnett Square? Specify the data you used.
Transcribed Image Text:Table 1: Expected Probabilities for Huntington'sDisease Genotype Genotype Phenotype Genotype probability as a percent HH Hh hh probability as a fraction Table 2. Data for Huntington's Disease Genotype Total # (Total # HH Hh h. What are the chances a child will have Huntington's Disease? Report data as a percentage: as a fraction: We are going to test the ratio of offspring given the parental genotypes above for Huntington's Disease by using a coin toss. The procedure is: 1. Obtain two coins. One represents the possible genotype(s) of the egg. The other represents the possible genotype(s) of the sperm. 2. Get one coin that represents the gametes of the mother. Each side of the coin represents one allele in a single gamete. Repeat for the father. 3. One student represents the mother and will flip the mother's coin. A second student represents the father and will flip the father's coin at the SAME time. 4. Note the two gametes that are face up. This represents the genotype of the offspring. Tally this genotype in the table below. 5. Repeat steps 1-4 24 times. hh Phenotype probability as a fraction genotype after 24 tosses genotype /24) X 100 in % Phenotype probability as a percent Probability Phenotype Total # from phenotype after 24 Punnett Square in % tosses (total # phenotype /24) x 100 in % Probability from Punnett Square in % Did your results from the coin tosses support your prediction from the Punnett Square? Specify the data you used.
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