FIGURE 17.8 Polson Oak Dermatitis This skin reaction results from delayed-type hypersensitivity. A hapten from poison oak combines with skin proteins. First exposure Subsequent exposures activate memory cells 1 Dendritic cells present the hapten:peptide complex to T cells. 3a Helper T cells activate macrophages presenting hapten:peptide complex. 3b Cytotoxic T cells destroy skin cells presenting hapten:peptide complex. Hapten:peptide Dendritic cell Naive helper T cell Naive cytotoxic T cell Macrophage Skin cell 2 T-cell activation, proliferation, and differentiation increases the population of T cells that recognize the hapten:peptide complex. Cytotoxic T cell Cytokines Helper T cell Naive helper T cell Naive cytotoxic T cell Activated macrophages release inflammatory mediators. 5 A rash appears after 24 hours, reaching a peak at 48–72 hours after exposure. Effector T cells Macrophage Memory cells Inflammatory mediators

FIGURE 17.8 Polson Oak Dermatitis This skin reaction results from delayed-type hypersensitivity. A hapten from poison oak combines with skin proteins. First exposure Subsequent exposures activate memory cells 1 Dendritic cells present the hapten:peptide complex to T cells. 3a Helper T cells activate macrophages presenting hapten:peptide complex. 3b Cytotoxic T cells destroy skin cells presenting hapten:peptide complex. Hapten:peptide Dendritic cell Naive helper T cell Naive cytotoxic T cell Macrophage Skin cell 2 T-cell activation, proliferation, and differentiation increases the population of T cells that recognize the hapten:peptide complex. Cytotoxic T cell Cytokines Helper T cell Naive helper T cell Naive cytotoxic T cell Activated macrophages release inflammatory mediators. 5 A rash appears after 24 hours, reaching a peak at 48–72 hours after exposure. Effector T cells Macrophage Memory cells Inflammatory mediators

BIOLOGY:CONCEPTS+APPL.(LOOSELEAF)

10th Edition

ISBN:9781305967359

Author:STARR

Publisher:STARR

Chapter34: Immunity

Section: Chapter Questions

Problem 16SA: Match the immunity concept with the best description. ___anaphylactic shock a. recognizes antigen...

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