Coronavirus from bats to animals, sequence comparison: Note: dots mean amino acid is the same as the one in the top sequence. Human Virus AGNNPLQTYVIACQDGGERRAAQDMFSAKKGGQTPAYWGC Civet Cat Virus G..... ......K....E.....R. .W. Pangolin Virus GA.Q....W..G....C.L..V.E....Q.. Bat Virus B Bat Virus AG .A.Q....W..G....C.L.. .....K. Y.. .N.G.T.A .2.. .N.G.T.A .R.......Y.. A researcher isolates a coronavirus from humans that they believe came from Bat virus A or Bat virus B. They also think the virus may have first gone through pangolins or civet cats. Shown above is an amino acid sequence comparison in the region of the virus spike protein that binds to the cell receptor. All viruses are compared to the human virus with colored dots indicating the same amino acid at that position and letters representing the amino acid change at the particular position. Answer the questions below using the figure. Question 1 (3 points). Does this data support the idea that the human virus is derived from a bat virus that that first went through one of the animal hosts? Explain briefly. Question 2 (2 points). Based on this information, which virus is the most likely to have been the closest ancestor to the human virus? Explain briefly.
Coronavirus from bats to animals, sequence comparison: Note: dots mean amino acid is the same as the one in the top sequence. Human Virus AGNNPLQTYVIACQDGGERRAAQDMFSAKKGGQTPAYWGC Civet Cat Virus G..... ......K....E.....R. .W. Pangolin Virus GA.Q....W..G....C.L..V.E....Q.. Bat Virus B Bat Virus AG .A.Q....W..G....C.L.. .....K. Y.. .N.G.T.A .2.. .N.G.T.A .R.......Y.. A researcher isolates a coronavirus from humans that they believe came from Bat virus A or Bat virus B. They also think the virus may have first gone through pangolins or civet cats. Shown above is an amino acid sequence comparison in the region of the virus spike protein that binds to the cell receptor. All viruses are compared to the human virus with colored dots indicating the same amino acid at that position and letters representing the amino acid change at the particular position. Answer the questions below using the figure. Question 1 (3 points). Does this data support the idea that the human virus is derived from a bat virus that that first went through one of the animal hosts? Explain briefly. Question 2 (2 points). Based on this information, which virus is the most likely to have been the closest ancestor to the human virus? Explain briefly.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Transcribed Image Text:Coronavirus from bats to animals, sequence comparison:
Note: dots mean amino acid is the same as the one in the
top sequence.
Human Virus AGNNPLQTYVIACQDGGERRAAQDMFSAKKGGQTPAYWGC
Civet Cat Virus G.....
......K....E.....R.
.W.
Pangolin Virus GA.Q....W..G....C.L..V.E....Q..
Bat Virus B
Bat Virus AG
.A.Q....W..G....C.L..
.....K.
Y..
.N.G.T.A
.2..
.N.G.T.A
.R.......Y..
A researcher isolates a coronavirus from humans that they
believe came from Bat virus A or Bat virus B. They also
think the virus may have first gone through pangolins or
civet cats. Shown above is an amino acid sequence
comparison in the region of the virus spike protein that
binds to the cell receptor. All viruses are compared to the
human virus with colored dots indicating the same amino
acid at that position and letters representing the amino
acid change at the particular position. Answer the
questions below using the figure.
Question 1 (3 points). Does this data support the idea that
the human virus is derived from a bat virus that that first
went through one of the animal hosts? Explain briefly.
Question 2 (2 points). Based on this information, which
virus is the most likely to have been the closest ancestor to
the human virus? Explain briefly.
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