Please solve Dr. Pradeep Patra, Dr. Virander Chauhan, and their colleagues assessed children in 2,087 villages in theIndian state of Chhattisgarh for their sickle cell anemia genotype. Sickle cell anemia is coded for by the tallele. Individuals who are tt have the more severe illness phenotype of sickle cell disease while Ttindividuals have a moderate illness phenotype called sickle cell trait. Individuals who are TT do not havesickle cell anemia.Of the 359,823 children assessed, 33,467 were Tt and only 747 were tt. The remaining 325,609 childrenwere TT.We will use these data to answer the following 6 questions.Calculate the total number of alleles for this gene assessed in thesample of children. DO NOT ROUND.

The alleles are the alternative forms of a gene that are located on the same locus of a homologous…

Answered: Dr. Pradeep Patra, Dr. Virander…

Curren'S Math For Meds: Dosages & Sol

11th Edition

ISBN:9781305143531

Author:CURREN

Publisher:CURREN

Chapter9: Parenteral Medication Labels And Dosage Calculation

Section: Chapter Questions

Problem 2.2P

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Sickle cell anemia is a genetically inherited autosomal recessive trait in which results in a condition that there are not enough healthy red blood cells to carry oxygen throughout the body due to the production of red blood cells that are sickle shaped. The frequency of the sickle cell condition is as high as 10% in Central Africa compared to 0.5% in the United States. Calculate the frequency of the normal and carries of the sickle cell condition.
The following scenario can be seen on Ch 29 Clinical case study on Heredity (27-year-old with normal pregnancy): Mrs. Rodriguez’ blood type is type O, and her husband’s is type A. She is currently pregnant and she would like to know what type of blood her baby will have. For discussion 7 please answer the following questions: What are the genotype and phenotype of Mrs. Rodriguez? What are the genotype and phenotype of Mr. Rodriguez, given that Mr. Rodriguez’s mother has O blood type and his father has A blood type? (use Punnett Square on your worksheet to find out the genotype of Mr. Rodriquez) What is the probability that Mrs. Rodriguez’s baby will have O blood type? A? B? AB? (use Punnett Square as your worksheet) Type O =______% Type A = _____ % Type B =______% Type AB =______%
Sickle cell disease (SCD) affects millions of people throughout the world; the CDC "Centers for Disease Control and Prevention" estimated that in the United States: SCD affects approximately 100,000 Americans. SCD occurs among about 1 out of every 365 Black or African-American births. SCD occurs among about 1 out of every 16,300 Hispanic-American births. About 1 in 13 Black or African-American babies is born with sickle cell trait (SCT). What do sickle cells mean? And how does this disease affect the human body? Why do Some experts state it can have some benefits?
Another couple is concerned their child will be born with sickle cell anemia. The woman does not have sickle cell anemia. The woman’s mother had sickle cell anemia and her father was a carrier of the sickle cell gene. The man knows that he is not a carrier of the sickle cell gene. What is the probability that the child will be a carrier of sickle cell anemia? please include a punnett square
What is the genotype of a person who has sickle cell disorder and provide a key that identifies what each allele in the genotype represents. (For example, B might represent the normal allele and b might represent the disordered allele) answer can be basic but understandable.
BACKGROUND: Sickle cell disease is caused by a change in the gene for hemoglobin, which is the oxygen-carrying protein in red blood cells. Individuals who are homozygous for the sickle cell trait often cannot endure exercise. Individuals who are heterozygous for the trait can have sickle cell attacks under extreme conditions. Normal individuals (genotype: Hbnorm Hbnorm ) have only normal hemoglobin. Homozygous sickle cell individuals (genotype: Hbsc Hbsc ) 'have only sickle cell hemoglobin. Heterozygous individuals (genotype: Hbnorm Hbsc ) have both normal and sickle cell hemoglobin. terry Smith collapsed while running a race for his track team. A doctor said he had a sickle cell attack. Genetic tests were run on several family members. The test results are shown below. An X indicates that form of hemoglobin in red blood cells. PROBLEM: How can you determine the genotypes of people in a family? Subject Normal Hemoglobin Sickle Cell Hemoglobin Jerry Jerry's brother Jerry's younger…
Sickle anemia is a favorable mutation. There is only one amino acid different in sickle haemoglobin (S) as compared with normal haemogloblin (A). Persons with sickle cell trait (AS) are able to survive in malarious areas. A couple each having sickle cell trait have five children. What is the probability that they will have a child with sickle disease?
A prospective groom, who is unaffected, has a sister with cystic fibrosis (CF), an autosomal recessive disease. Their parents are normal. The brother plans to marry a woman who has no history of CF in her family. What is the probability that they will produce a CF child? They are both Caucasian, and the overall frequency of CF in the Caucasian population is 1/2500—that is, 1 affected child per 2500. (Assume the population meets the Hardy– Weinberg assumptions.)
what are the other system of blood typing besides ABO group? Give at least 3 and what are the modes of inheritance (Autosomal dominant, recessive or sex linked dominant, recessive or multifactorial or mitochondrial) of these blood groups?
The following is a summary of the possible sickle-cell genotypes and phenotypes: AA - cojmpletely normal AS - sickle-cell trait (this person has a combination of normal hemoglobin and the abnormal, sickled form of hemoglobin) SS - sickle-cell anemia (all abnormal hemoglobin) If both parents and heterozygous for sickle-cell disease, what are the possible genotypes and phenotypes for their children?
In humans, hemophilia is a sex-linked trait. Females can be normal, carriers, or have the disease. Males will either have the disease or not (but they won’t ever be carriers). X H X H = female, non-hemophilic X H X h = female, carrier X h X h = female, hemophilia X H Y = male, non-hemophilic X h Y= male, hemophiliac a.) Show the cross of a man who has hemophilia with a woman who is a carrier. What is the probability that their children will have the disease? b.) A woman who is a carrier marries a non-hemophilic man. Show the cross. What is the probability that their children will have hemophilia? What sex will a child in the family with hemophilia be? c.) A woman who has hemophilia marries a non-hemophilic man. How many of their children will have hemophilia, and what is their sex?
Note there are no cells on this panel that have a double dose (homozygous) of the K antigen. Which of the following statements is true regarding the K+k- phenotype? Question 6 options: A) The phenotype is rare due to the high prevalence of the k antigen in the population. B) The phenotype is uncommon but does occur in about 10% of the population. C) The phenotype occurs in about 50% of the population. D) Although the phenotype is not represented on this antibody panel, it is fairly common in the population.

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