Describe two different ways that histone modifications may alter chromatin structure.

Q: reduction in histone acetylation and reduced gene transcription. Given this information, which of…

A: Transcription is a highly controlled process and it requires the presence of enzymes polymerase and…

Q: Briefly explain how patterns of DNA methylation are transmitted across cell divisions.

A: DNA methylation is a biological mechanism that attaches methyl groups to DNA molecule. Methylation…

Q: Explain how methylation of cytosine nucleotides can affect gene expression in one way. Explain how…

A: DNA is a polymer made up of a nucleotide monomer. The double strands of the DNA are joined through a…

Q: Consider the Rho-dependent terminator sequence 5’CCCAGCCCGCCUAAUGAGCGGCCUUUUUUUU-3’. What affect…

A: The mutation is the change in the nucleotide sequence of the DNA. The point mutation is the mutation…

Q: The rb gene encodes a protein that inhibits E2F, a transcriptionfactor that activates several genes…

A: Abnormal and unnecessary growth of cells termed cancer. Mutations in DNA causes cancer. In the…

Q: What has happened to the chromatin in the diagram? What regulatory proteins binds to what part of…

A: DNA is a double helical structure, which is wrapped around histones.  histones are proteins found in…

Q: Briefly describe how mitotic recombination can result in loss of heterozygosity (LOH) at tumor…

A: Loss of heterozygosity (LOH) is the loss of one parent's contribution to cell and can be caused by…

Q: You are interested in the effects of mutations on the expression of a human protein- encoding gene…

A: Functional part of a DNA that synthesizes any functional product in the form of mRNA and proteins is…

Q: Members of a family are affected by a hereditary inflammatory and immunodeficiency disease. The…

A: Co-dominance:Co dominance is when the both genetypic alleles are seen in phenotype. Dominant…

Q: Mutations in genes encoding chromatin-remodeling complexes have been identified in high frequencies…

A: A mutation is a change that occurs in the deoxyribonucleic acid (DNA)when it is damaged or changed…

Q: Select whether each of the components are associated with eukaryotic or prokaryotic transcription.…

A: The expression of the genetic material occurs generally through the production of proteins. This…

Q: Although each cell in your body contains the same set of genes, the genes that are “turned on”…

A: DISCLAIMER FOR MULTIPLE   Since you have asked multiple question, we will solve the first question…

Q: cell is homozygous for a LOF mutation in the histone acetyltransferase (HAT) gene. Which of the…

A: HAT stands for Histone acetyl transferase. The LOF refers to the loss of function mutation. If a…

Q: “DNMT3L Connects Unmethylated Lysine 4 of Histone H3 to de novo Methylation of DNA,” the authors…

A: Figure a and b of the paper “DNMT3L Connects Unmethylated Lysine 4 of Histone H3 to de novo…

Q: Explain

A: The process by which information encoded in a gene is used to control the assembly of a protein…

Q: A cultured mouse cell line has a mutation in a gene encoding a ribosomal protein. The mutant protein…

A: Chaperones are a kind of protein with similar properties that aid in protein folding. These proteins…

Q: Describe the appearance of a Drosophila embryo, in which the knirps gene protein-coding sequence has…

A: Gene is a functional unit of heredity. A gene is a sequence of nucleotides in genome that codes for…

Q: Many genes generate different products depending on the type of cell expressing the gene. How is…

A: The process of generation of different protein products from the same pre-mRNA transcript is called…

Q: Define about mechanisms of epigenetic modificationsto the genome ?

A: Gene is known to be the unit of heredity of all living organisms. The genetic information of an…

Q: DNA methylation is considered an epigenetic phenomenon because the pattern of methylation can be…

A: Epigenetics is considered as a study of certain gene expressions, which is heritable.

Q: A plant geneticist was examining the inversion mutation XI 501 in barley where a segment of DNA is…

A: Any alteration occurring in the DNA sequence of an organism is known as mutation.

Q: How many of the mutations listed below would lead to excessive cell growth when the cell was either…

A: Excessive growth occurs when a cell continuously divides and when there is no cell cycle arrest. Myc…

Q: If histones are acetylated on a lysine amino acid (an epigenomic mark), are genes in this region…

A: Epigenetics is the branch of genetics that deals with changes in gene expression (no change in the…

Q: What is cell differentiation? Discuss the role of myogenic bHLH proteins in the differentiation of…

A: Proteins are the building blocks of the body and they are composed of chains of amino acids. Amino…

Q: Discuss the role of chromatin and modification of chromatin structure in controlling eukaryotic gene…

A: The mechanism of encoding of proteins by a gene which regulates cellular functions is known as gene…

Q: Some cancers are consistently associated with the deletion of a particularpart of a chromosome. Does…

A: Proto-oncogenes are normal genes that encode for proteins required for the promotion of cell cycle.…

Q: How does chemical modification of the histones lead to changes in chromatin structure? Choose all…

A: Chromatin It refers to the complex of DNA and proteins that forms chromosomes in the nucleus of…

Q: c) You use chromatin immunoprecipitation to measure the location and amount of transcription factors…

A: Transcription factors are protein molecules which bind to specific DNA sequences to regulate gene…

Q: You are working in a lab studying Progeria. You design an expression vector containing a mutated…

A: A vector refers to the plasmid that carries a gene of interest into the host cells. Expression…

Q: The following diagram show what is required for an active promoter of a gene of interest, where:A1 =…

A: Based on the given diagram, here are the predictions:Chromatin conformation: EuchromatinMethylation…

Q: Which of the following scenarios will cause the maternal X chromosome to condense into a Barr body?…

A: The following scenarios will cause the maternal X chromosome to condense into a barr body:. Option 2…

Q: A gene, which we will call gene C, can be epigenetically modified in such a way that its expression…

A: Introduction: Gene is the structural and functional unit of inheritance or heredity which transfers…

Q: Histone methylation alters the chromatin structure with varied effects depending on the specific…

A: Chemical modification of all histone proteins occurs. The modification that occurs at histone…

Q: DNA methylation is considered an epigenetic phenomenon because the pattern of methylation can be…

A: Epigenetics refers to the phenomenon where traits can be inherited through reverdible changes in…

Q: In humans, the average length of a gene on chromosome 7 is 69,000 base pairs, but the average mRNA…

A: DNA( deoxyribonucleic acid) is the double-stranded molecule that is the genetic material in most…

Q: 1. Heterochromatin is typically gene-rich and composed of loosely-packed DNA that is…

A: “Since you have asked multiple question, we will solve the first question for you. If you want any…

Q: A disease is caused by having no functional protein produced from the kip gene. An individual has…

A: Mutations are alterations in the DNA sequence of an organism. Small changes, such as adding or…

Q: Q. The nuclear membrane disintegrates late in prophase of mitosis in most eukaryotic cells. Once the…

A: DNA polymerase is found in the cytoplasm outside of the nucleus.  So we can say that options C, D,…

Q: Describe how the compaction of nucleosomes into a knot-like structure couldsilence gene expression.

A: The gene expression is a process through which the information from deoxyribonucleic acid (DNA) is…

Q: The study of Epigenetics includes which of the following? (Choose all that apply)

A: 1.The vertical transmission of histone modifications 3.How Histone acetylation affects gene…

Q: Eukaryotic transcriptional repressors may act by   Choose an answer below competing for a binding…

A: Eukaryotic transcriptional repressor : These are the proteins which bind to the specific sites of…