describe the outcome of EGFR inhibition as well as the differences between erlotinib and panitumumab’s mechanisms of action. EGFR- driven cancer cells can become resistant to tyrosine kinase inhibitors. Explain the two types of EGFR blockade acquired resistance and propose a subsequent treatment option.

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A: Chronic, myeloproliferative disorder of increased red blood cell (RBC) mass, leukocytosis,…

Q: Discuss the place in therapy of beta 2 agonists in asthma and describe their mode of action.

A: Beta 2 agonists therapy in asthma treatment.

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A: Cancer is basically the uncontrolled growth and division of cells without the death of the cells in…

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Q: TNF-alpha treatment of prostate carcinoma, LNCAP cells decreases cell survival as shown in the graph…

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Q: It has been shown that unusual activation of TGFb signaling pathway is associated with breast cancer…

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Q: Discuss the challenges to producing anticancer drugsthat counteract the effects of mutations in…

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A: Introduction: Neurotransmitters are the chemical substances secreted from the end of the nerve cell…

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Q: Estrogen receptor antagonists inhibit tumors by: 1) blocking estrogen binding to receptors 2)…

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Q: Why is basal cell carcinoma (e.g., skin cancer) more prevalent than osteosarcoma (e.g., bone…

A: The term cancer basically means malignant tumors. Malignant tumors are characterised by…

Q: The serotonin molecule has some remarkable properties. It is synthesized by two different two…

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A: Eph receptors are a class of receptors that are activated in response to interaction with Eph…

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Genomic studies

Genomic studies (genomics) is the study of the whole genome of an organism. Using bioinformatics and high-performance computing, genomic researchers examined massive amounts of deoxyribonucleic acid (DNA)-sequence data to discover variations or mutations that affect drug response, health, or disease. Genomics is a much younger discipline than genetics, having only emerged in the last few decades as a result of technological advancements in DNA sequencing and computational biology.