Describe the following techniques for determining gene or protein function with advantages disadvantages and limitations. i)forward genetics(random mutagenesis) ii)reverse genetics(altering the function of particular gene) iii)genetic analysis(double or higher order mutant combination)

Q: 5. a) Briefly explain three advantages that CRISPR has over earlier methods of genetic manipulation…

A: Introduction:- Genome editing is an extremely strong tool that can help you answer a wide range of…

Q: organisms

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Q: For a coding gene, purifying (negative) selection will result in more synonymous (silent) site…

A: Purifying selection is the most predominant form of natural selection or negative selection. As it…

Q: Name two commonly used vectors in genetic engineering.

A: Vectors are the DNA molecules which are used to insert a foreign gene into the host cell to make the…

Q: Why Gene-prediction programs are used ?

A: In a DNA sequence, where those codons might fall even where a functional protein might be present or…

Q: List three clinical indications for chromosome and/or genome analysis and why the process might be…

A: Genome analysis refers to the study of an organism's entire genetic information, or genome. It…

Q: There are four possible observations that suggest an error occurred in a PCR reaction: a) Sequence…

A: PCR reaction is a method used to amplify a small sample into millions of small ones which help the…

Q: Within genomics, genetic engineering and gene therapy are two topics that are quite comparable. What…

A: Genomics is the study of an organism's entire genetic complement (the genome). It sequences,…

Q: In a clinical context, doctors are evaluating a therapy for a new patient (say patient B) that they…

A: In the setting of assessing treatment for a modern patient (patient B) who may develop comparable…

Q: All of the following are true about the design of the Beadle and Tatum experiment (one gene one…

A: The "one gene, one enzyme" theory was supported by George Beadle and Edward Tatum's demonstration…

Q: ISSR is generally a dominant STS DNA marker. Nonetheless, with validated experimental evidence (e.g.…

A: Codominant marker are inherited by both the parents to next generation in equal proportion. When…

Q: Explain the basic techniques used to manipulate genetic material

A: Genetic Material:         A cell or an organism comprises information carrier materials found in the…

Q: outline HOW to clone and identify a new gene!

A: Gene clonning is technique of genetic engineering where a gene of intrest is isolated from its DNA…

Q: Fill in the Table  Broad Topic: Specific Topic: What is known: Experimental Question:…

A: This work explores single-cell level gene expression mistakes in Bacillus subtilis. The study looks…

Q: What are ‘Selectable marker’? What is their use in genetic engineering?

A: Genetic engineering is a technique to manipulate the genetic content of an organism resulting in…

Q: Exaplain the two methods to study the contents of transcriptomes which are microarray analysis and…

A: Transcriptome analysis may be used to find novel genes and isoforms that are not already cataloged…

Q: Describe the medical applications of human gene therapy in the following diseases: Haemophilia,…

A: Gene therapy is a treatment of a disease where the genetic material is transferred into human cells.…

Q: If you wanted to make a mouse model for any of the following human genetic conditions (a–d),…

A: Since we only answer up to 3 sub-parts, we’ll answer the first three. Please resubmit the question…

Q: Using the diagram below describe the significance of DNA sequencing for identification of mutations.

A: DNA sequencing is typically the process of determining the nucleic acid sequence the order of…

Q: 13. An investigator is studying epigenetic markers in patients with retinoblastoma. It is most…

A: Retinoblastoma is a form of cancer that develops in the retina of the eye. It is rare and life…

Q: (6) Which of the following descriptions regarding human genetic variations is correct? A) Unlike…

A: SNPs may effect promoter activity or gene expression, messenger RNA ,conformation stability, and…

Q: lease write in digital format To mention: a) Types of mutations b) Mutagenic agents c) Genetically…

A: Types of mutations :  1. Point mutations  a) Substitution  b) Insertion  c) Deletion  2. Chromosomal…

Q: Cause Would result in the following error Unbalanced nucleotide concentrations a) Sequence errors in…

A: The polymerase chain reaction is the method that is used for making copies of DNA, it is developed…

Q: 3) You have identified an interesting mutant in gene P. Using a Punnett square, demonstrate the…

A: The pure breeding lines of mutant and wild type organism must be crossed to determine if the…

Q: please solve the  following: (a)Explain how a mutation effects a genotype. (b) Explain how a…

A: The genotype refers to the hereditary material passed among generation, and the phenotype is…

Q: gene mutation

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Q: Should the exposome field focus exclusively on measuring chemicals derived from exogebeous sources…

A: The term "exposome" describes all of an individual's lifetime environmental exposures, including…

Q: 1)  Dr. Velazquez considers targeted mutagenesis of DNA ligase. What would that do?   a)  Prevent…

A: INTRODUCTION DNA ligase DNA ligase is an enzyme that can join DNA fragments by catalyzing the…

Q: Outline different strategies for identifying gene sequences.

A: Genome is the study of all genes present in the organism. Gene is a unit of heredity that is…

Q: Give a step by step method and diagram of how reversible terminator sequencing works.

A: The reversible terminator sequencing or Illumina dye sequencing is a technique used to determine the…

Q: #8) Compare methods for constructing homologous recombinant transgenic mice and yeast?

A: The process of homologous recombination involves the transfer of DNA (deoxyribose nucleic acid)…

Q: Briefly answer the question: Exome sequencing to identify a mutation that could cause a particular…

A: Primary findings are the testing results which are obtained and provide required information about…

Q: Using the information provided below, which of the individuals A and B have: i) Genotypic change i)…

A: DNA is made up of four nucleotides A, T, C and G. Mutation is the change in the genetic sequence or…

Q: What is Central Dogma of Molecular Biology and how this concept is used in the development of…

A: Genetically modified organisms are those that have been modified by humans in order to show those…

Q: Genetic engineering and gene therapy are similar fields within genomics. What do they have in common…

A: Genetic engineering and gene therapy are similar fields with genomics. They are both similar as they…

Q: Genome annotation refers to ... 1.) lining up overlapping regions in short shotgun sequencing reads…

A: Introduction:- Genome consists of all the genetic and biological information of an individual…

Q: 8. A mutant that has a nutritional requirement for growth is an example of a(n) A) heterotroph B)…

A: Mutation in biology is a change in the extrachromosomal genetic material, the virus, or the…

Q: 4) List 3 things that a potential vector must have in order to be useful. 5) Sometimes the gene for…

A: 1.Three things that a potential vector must have in order to be useful is viral replication origin,…

Genomic studies

Genomic studies (genomics) is the study of the whole genome of an organism. Using bioinformatics and high-performance computing, genomic researchers examined massive amounts of deoxyribonucleic acid (DNA)-sequence data to discover variations or mutations that affect drug response, health, or disease. Genomics is a much younger discipline than genetics, having only emerged in the last few decades as a result of technological advancements in DNA sequencing and computational biology.