Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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Defines the situation when all receptor binding sites are occupied by a messenger
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- Both rhodopsin in vision and the muscarinic acetylcholine receptor in cardiac muscle are coupled to ion channels via G proteins. Describe the similarities and differences between these two systems.arrow_forwardBriefly explain the difference between a receptor antagonist and a receptor inverse agonist. Describe both the resulting receptor conformation as well as the signal transduction.arrow_forwardwhat is an evolutionarily conserved class of receptor, consisting of an integral membrane receptor protein coupled to an intracellular protein that transmits signals to the interior of the cell.arrow_forward
- Which is a correct explanation of an aspect within G protein signaling pathway? ATP powers the G protein to cause it to move and activate an enzyme O GTP activates the G protein causing it to move to activate the next protein O The receptor is active when bound to GTP GTP causes the G protein to activate and bind to the receptorarrow_forwardDescribe the action of neurotransmitters at channellinked and G protein–linked receptors.arrow_forwardwhat is a receptor and give one example of where a receptor is found, explaining its role is in monitoring homeostasisarrow_forward
- Mr PL was administered Drug A that acts on a particular receptor. Unfortunately, it was given in overdose and produced an adverse effect. Drug B is then administered which blocks that receptor. The effect of drug B results in a reduction in the effect of drug A. Comment on if Drug B is acting competitively (reversibly) or non-competitively (irreversibly)? Provide one suitable clinically relevant example of such interaction.arrow_forwardDescribe the biochemical signaling steps by which activation of the NMDA receptor causes the postsynaptic cell to fire larger EPSPs.arrow_forwardBriefly describe what is signal amplification process using cAMP as the second messenger for examplearrow_forward
- Describe the signal transduction pathway that lipid-soluble messengers use.arrow_forwardList several roles of membrane receptors and that of G protein–linked receptors.arrow_forwardOf membrane-bound receptors and nuclear receptors, which is betteradapted for mediating a response that lasts a considerable length oftime, and which is better for mediating a response with a rapid onset andshort duration? Explain why.arrow_forward
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