Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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- What feature(s) of this pedigree indicate(s) X-linked recessive inheritance?arrow_forwardSuppose a woman who is a carrier of sickle-cell trait (making her a heterozygote) has children with a man who is totally healthy and does not carry the gene for sickle-cell trait at all. Which one of the following is true about their potential children? (Draw a Punnett square on scratch paper if it helps you.) A) None of their children will have sickle-cell disease. B) All of their children will have sickle-cell disease. C) All of the couple's children would be heterozygous carriers like the mother.arrow_forwardBelow is a pedigree chart for a family that has a history of Alkaptonuria. Individuals infected with this condition can have darkened skin, brown urine, and can suffer from joint damage and other complications. Given this pedigree answer the following questions. Given the data in the pedigree chart is this genetic condition autosomal dominant or autosomal recessive? What are the genotypes for #1, #2, and #3? If either of the 4th generation "aa" females were to mate with a homozygous dominant male would any of their offspring illustrate the phenotype? Why or why not?arrow_forward
- In humans, red-green color-blindness is a recessive X-linked trait. A man with red-green color- blindness marries a normal-vision woman whose father was color-blind. As the genetic counselor, construct a Punnett square to determine the genotypic and phenotypic possibilities of their children. orange is due to heteroz means In human, assume that albinism is an autosomal recessive characteristic while hemophilia is X-linked recessive. An albino nonhemophiliac man has children with a normally-pigmented nonhemophiliac woman whose father was a hemophiliac and whose mother was albino. Calculate the phenotypes of the children they could produce.arrow_forwardMary has hemophilia, an X-linked recessive trait. From which of the following individuals could Mary NOT have inherited a hemophilia allele? O Her father O Her father's mother O Her mother's mother O Her father's father O Her mother's fatherarrow_forwardPlease do the pedigree in the attached picturearrow_forward
- Sickle cell anemia is caused by an individual carrying two recessive copies of the hemoglobin gene (hemoglobin gene is labeled Hb, and the recessive version is Hbs). Thus, to have sickle cell anemia, a person must have the genotype HbSHbS. A person that is HbAHbA carries two copies of the normal hemoglobin gene and does not have sickle cell anemia. A person that is heterozygous (HbAHbS) produces enough normal hemoglobin to not have sickle cell anemia but is also resistant to malaria. People that are heterozygous are called “carriers” because they carry the recessive allele but do not express the recessive phenotype. a. A couple are both resistant to malaria but do not have sickle cell anemia. Draw a Punnett square to represent this cross. b. What is the probability that the couple has three children where one child does not have a recessive allele, one child is resistant to malaria and does not have sickle cell anemia, and one child has sickle cell anemia?arrow_forwardHemophilia is due to a sex-linked gene. It is recessive and found on the X chromosome. A woman who is a carrier for hemophilia marries a normal man. What will be the possible phenotypes of their children? (use the letter “H”)arrow_forwardClara has polydactyly, an autosomal dominant that is 80% penetrant. Clara inherited her polydactyly from her mother, her father had no polydactyly in his family. She has an extra toe on her left foot. Her husband Ralph has no polydactyly in his family. A) What is the chance that Clara will have a child that will inherit polydactyly? B) What is the chance that the child will express polydactyly. You can leave these as un-calculated equations.arrow_forward
- The pedigree chart provided below traces the occurrence of a disease through the generations of a family. Determine what type of inheritance pattern this disease has.arrow_forwardHemophilia, disease in which the blood lacks a clotting factor, is caused by an X linked recessive gene. Joe doe not have hemophilia and Lucille is heterozygous for the condition. What is the chance that their MALE child will have hemophilia? (Note: you are calculating the probability for their MALE children only, in other words if they have 1 male child, what is the probability that he will be born with the disease?) 0% 1/4 or 25% 2/4 or 50% 3/4 or 75% 4/4 or 100%arrow_forwardThe Delacour family is descended from the Veela race, a semi-human, semi-magical humanoid people reminiscent of the Sirens in Greek mythology with special powers. Imagine that being a Veela and having these powers is a X-Linked Dominant trait that is passed on genetically. (Hint: Use the Punnett Square.) What are the possible genotypes for Fleur and Bill’s daughter, Victoire? What are the genotypic frequencies related to the female children (in percentage format)? What is the likelihood (in percentage format) that Victoire would express Veela powers?arrow_forward
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