Congenital pulmonary alveolar proteinosis is a rare lung disease in humans. The disease is caused by a recessive mutation in the gene CSF2RA. CSF2RA is located within a pseudoautosomal region of the X and Y chromosomes. The normal allele is notated as Cnorm, and the mutant allele is notated as Cmut. Suppose that a woman with Cnorm on both X chromosomes (XCnormyCnorm) has children with a man with Cmut on the X chromosome and Cnorm on the Y chromosome (XCmutyCnorm Select all possible genotypes of their offspring Select all possible genotypes of their offspring for males. for females. O xCnormy Cnorm O xCnormyCnorm O xCnormyCmut O xCmutyCmut O xCmutxCmut O xCmutyCnorm O xCnormyCmut

Human Anatomy & Physiology (11th Edition)
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Congenital pulmonary alveolar proteinosis is a rare lung disease in humans. The disease is caused by a recessive mutation in the
gene CSF2RA. CSF2RA is located within a pseudoautosomal region of the X and Y chromosomes. The normal allele is notated
as Cnorm, and the mutant allele is notated as Cmut.
Suppose that a woman with Cnorm on both X chromosomes (XCnormyCnorm) has children with a man with Cmut on the X
chromosome and Cnorm on the Y chromosome (XCmutyCnorm
Select all possible genotypes of their offspring
Select all possible genotypes of their offspring for males.
for females.
O xCnormy Cnorm
O xCnormyCnorm
O xCnormyCmut
O xCmutyCmut
O xCmutxCmut
O xCmutyCnorm
O xCnormyCmut
Transcribed Image Text:Congenital pulmonary alveolar proteinosis is a rare lung disease in humans. The disease is caused by a recessive mutation in the gene CSF2RA. CSF2RA is located within a pseudoautosomal region of the X and Y chromosomes. The normal allele is notated as Cnorm, and the mutant allele is notated as Cmut. Suppose that a woman with Cnorm on both X chromosomes (XCnormyCnorm) has children with a man with Cmut on the X chromosome and Cnorm on the Y chromosome (XCmutyCnorm Select all possible genotypes of their offspring Select all possible genotypes of their offspring for males. for females. O xCnormy Cnorm O xCnormyCnorm O xCnormyCmut O xCmutyCmut O xCmutxCmut O xCmutyCnorm O xCnormyCmut
Which genotype is associated with the disease phenotype for pulmonary alveolar proteinosis?
xCmuty Cnorm
xCnormyCmut
xCnormx Cmut
None of these.
Transcribed Image Text:Which genotype is associated with the disease phenotype for pulmonary alveolar proteinosis? xCmuty Cnorm xCnormyCmut xCnormx Cmut None of these.
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