Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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1. Compare the control of gene regulation in eukaryotes and prokaryotes in terms
of:
a. transcription
b. regulatory mechanisms and its components
2. Explain the evolutionary significance of mutations.
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- 28. Approximately 50 % of the human genome is composed of a. protein-coding genes b. ribosomal RNA genes c. mobile genetic elements like transposons and retrotransposons d. introns e. promoter sequences.arrow_forward1. Determine the effect of the following mutations on the DNA sequence. In each case, the mutation is described after the sequence (REFER TO THE SUPPLEMENTAL DOCUMENT FOR GUIDANCE TO THIS QUESTION). Adenine nucleotide (A shown in red below) was inserted into the DNA sequence at the position indicated by the arrow). Write out the sequence of the mutated DNA and the protein made from it. What is the effect of this mutation on the protein? (For example, how will the mutation affect the length and sequence of the protein? What about the function of the protein?) A 3' TACATGG'TTGTGCTAATT 5'arrow_forward8. In genetic screens of mutagenized yeast, temperature sensitive mutants defective in the secretory pathway (sec mutants) were identified. These mutants have helped scientists study the protein secretion pathway that is necessary/essential for life in eukaryotic cells. To identify sec mutants: mutagenized yeast cells were grown for 12 hours at low temperature, shifted to higher temperature for two hours, and then the population of cells were centrifuged in a density gradient. a. Mutagenized cells were first grown at the lower temperature and then shifted to the higher temperature. i. Why was the shift in temperature an important step of the experimental protocol? ii. Why would the experiment have been unsuccessful if the cells were grown exclusively at the higher temperature? b. After centrifugation, where would sec mutant cells be located compared to other cells in the population? Briefly explain why.arrow_forward
- 1. Suppose there was a mutation in the inducer of the lac operon, such that the inducer was unable to function. How would the lac operon be affected? Please explain your reasoning in 1-3 sentences.arrow_forward1. What happens during transcription? Possible sentence frame: Transcription is the process in which the information from converted into This happens by isarrow_forward1. Compare and contrast repressible and inducible operons. 2. Are genes for enzymes involved in anabolic processes usually repressible or inducible , why?arrow_forward
- 3. miR164 is a gene that encodes for a miRNA that targets a transcription factor. Describe in detail how, mechanistically, expression of miR164 could lead to altering the function of the transcription factorarrow_forward1. The research done by Gregor Mendel is important because it showed a. physical traits in bacteria are determined by chromosomes. b. chromosomes in pea plants separate during cell division. c. DNA is present in bacteria. d. physical traits in pea plants are passed between generations. 2. Transcription of the lacZ and lacy genes of the lac operon begins when a. the repressor is released from the promoter b. the repressor protein binds to the inducer c. RNA polymerase binds to the lacZ gene d. lactose binds to the operator 3. During DNA replication, the function of RNA primers is to: a. serve as a binding site for DNA ligase b. serve as starting points for DNA strand elongation by DNA polymerase III in prokaryotes c. serve as starting points for DNA strand elongation by DNA polymerase I in the 3' - 5' direction d. open replication bubbles 4. Which statement about purines is true? a. Each purine is base pair with a pyrmidine. b. They are adenine and guanine. c. They are nitrogenous bases…arrow_forward20. Genome imprinting can be the result of silencing genes by methylation of promoter DNA sequences. Which of the following is true? A. They directly inhibit RNA transcription. B. They directly inhibit protein translation. C. They directly inhibit nuclear pore transport. D. They directly inhibit ribosome assembly E. They reduce protein stability.arrow_forward
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