Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Related questions
Concept explainers
Question
Transcribed Image Text:**Predict the Level of Genetic Activity of the lac Operon**
In this educational section, we aim to predict the level of genetic activity of the lac operon, along with the status of the lac repressor and the CAP protein under various cellular conditions. The table below indicates the presence (+) or absence (−) of lactose and glucose in the cellular environment:
| Cellular Conditions | Lactose | Glucose |
|:---------------------:|:--------:|:--------:|
| a) | − | − |
| b) | + | − |
| c) | − | + |
| d) | + | + |
For each of the conditions (a, b, c, and d), we need to determine the following:
- Whether the operon is on, off, or at a basal level of activity?
- Is the lac repressor bound to the operator?
- Is the CAP protein bound to the CAP site?
### Detailed Explanations:
#### Condition a)
- **Operon:** On or off or basal?
- **Lac Repressor:** Bound to operator?
- **CAP Protein:** Bound to CAP site?
#### Condition b)
- **Operon:** On or off or basal?
- **Lac Repressor:** Bound to operator?
- **CAP Protein:** Bound to CAP site?
#### Condition c)
- **Operon:** On or off or basal?
- **Lac Repressor:** Bound to operator?
- **CAP Protein:** Bound to CAP site?
#### Condition d)
- **Operon:** On or off or basal?
- **Lac Repressor:** Bound to operator?
- **CAP Protein:** Bound to CAP site?
**Explanation:**
1. **Lactose (−) and Glucose (−)**: No lactose to induce the operon and low glucose leading to active CAP protein due to high cAMP levels.
2. **Lactose (+) and Glucose (−)**: Lactose present to induce the operon and absence of glucose will activate CAP protein.
3. **Lactose (−) and Glucose (+)**: No lactose to induce the operon and glucose presence will inactivate CAP protein.
4. **Lactose (+) and Glucose (+)**: Lactose present to induce the operon but high glucose will suppress CAP protein binding due to low cAMP levels.
Expert Solution
This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
Step by stepSolved in 2 steps
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- In the regulation of the tryophan operon in bacteria, the co-occurence of transcription and translation plays a key role regulating full activation of operon expression. Diagram and explain how during the conditions of high tryptophan concentration this system regulates the expression of genes in the operon.arrow_forwardThe lac operon contains three genes: lacZ, lacY, and lacA for ß-galactosidase, galactoside permease, and thiogalactoside transacetylase, respectively. The operon also contains a promoter site and an operator site. The regulatory gene includes the I gene for the Lac repressor protein and a promoter for that gene. regulatory gene DNA P₁ lacl gene The lac operon undergoes negative regulation. In the normal condition, the Lac repressor protein is active. Allolactose, an isomer of lactose, is the signal molecule that binds to the Lac repressor. P O Increase in gene products The I gene is disabled. Lactose is present in the cell. The Lac repressor dissociates from DNA. lac operon lacZ gene Determine which events will increase the concentration of lac gene products and which will decrease the concentration of lac gene products. Allolactose is not present in the cell. lacy gene lacA gene Decrease in gene products Allolactose binds to the Lac repressor protein. The Lac repressor remains bound…arrow_forwardConsider this strain of E. coli with lac operon alleles: IS pt o* z* y+ /T p* oCz- Y+ In a written response, briefly explain if beta-galactosidase AND permease will be expressed, and if so, will they be inducible or constitutive.arrow_forward
- There is a mutation in sequence of the lac operator that prevents the lac repressor from being able to recognize and bind to it. What would the status of transcription of the lac operon be under each of the following circumstances? Explain your answers. a-Lactose present, glucose present b-Lactose present, glucose absent c-Lactose absent, glucose present d-Lactose absent, glucose absentarrow_forward8&9arrow_forwardMolecular biology, please explain in detailarrow_forward
- . Listed in parts a through g are some mutations that were found in the 5′ UTR of the trp operon of E. coli. What will the most likely effect of each of these mutations be on the transcription of the trp structural genes? Q. A mutation that prevents the binding of the ribosome to the 5′ end of the mRNA 5′ UTRarrow_forwardMatch each description with the appropriate label (allo)Lactose binds to the lac repressor, causing it to release from the promoter CAP binds CAMP to stimulate transcripti of the lac operon ✓ [Choose ] positive control of an inducible gene negative control of an inducible gene [Choose]arrow_forward
arrow_back_ios
arrow_forward_ios
Recommended textbooks for you
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSON
Biology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStax
Anatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education, 
Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education