Chapter : Lipid Metabolism "It has been proposed that malonyl CoA may be one of the signals sent to the brain to decrease the appetite response. When mice are given a derivative of cerulenin (a fungal epoxide) named C75, their appetite is suppressed and they rapidly lose weight. Cerulenin and its derivatives have been shown to be potent inhibitors of fatty acid synthase (FAS). Suggest how C75 might act as a potential weight reduction drug" Thanks. Please write the answers clearly.

Chapter : Lipid Metabolism "It has been proposed that malonyl CoA may be one of the signals sent to the brain to decrease the appetite response. When mice are given a derivative of cerulenin (a fungal epoxide) named C75, their appetite is suppressed and they rapidly lose weight. Cerulenin and its derivatives have been shown to be potent inhibitors of fatty acid synthase (FAS). Suggest how C75 might act as a potential weight reduction drug" Thanks. Please write the answers clearly.

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter27: Metabolic Integration And Organ Specialization

Section: Chapter Questions

Problem 17P

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