A. Identify different types of organic reaction mechanims in the following metabolic pathways. 1. Catabolism of triacylglycerols- beta-oxidation pathway 2. Biosynthesis of fatty acids from Acetyl CoA 3. Glycolysis (from glucose to two molecules of pyruvate
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A. Identify different types of organic reaction mechanims in the following
1. Catabolism of triacylglycerols- beta-oxidation pathway
2. Biosynthesis of fatty acids from Acetyl CoA
3. Glycolysis (from glucose to two molecules of pyruvate)
4. Conversion of Pyruvate to Acetyl CoA
5.Citric acid cycle
6. Gluconeogensis pathway (pyruvate to glucose)
B. Identify at most 5 organic reactions for each metabolic pathway.
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- Identify different types of organic reaction mechanism (SN1, SN2, etc.) and reaction types (Addition, elimination, etc ) in the following metabolic pathways. 1. Catabolism of triacylglycerols- beta-oxidation pathway 2. Biosynthesis of fatty acids from Acetyl CoA 3. Glycolysis (from glucose to two molecules of pyruvate) 4. Conversion of Pyruvate to Acetyl CoA 5. Citric acid cycle 6. Gluconeogenesis pathway (pyruvate to glucose)Identify at most 5 organic reactions for each metabolic pathway. Metabolic pathways: 1. Catabolism of triacylglycerols- beta-oxidation pathway2. Biosynthesis of fatty acids from Acetyl CoA3. Glycolysis (from glucose to two molecules of pyruvate)4. Conversion of Pyruvate to Acetyl CoA5.Citric acid cycle6. Gluconeogensis pathway (pyruvate to glucose)Identify and draw different types of organic reaction mechanisms in the following metabolic pathways. 1. Catabolism of triacylglycerols-beta-oxidation pathway 2. Biosynthesis of fatty acids from Acetyl CoA 3. Glycolysis (from glucose to two molecules of pyruvate) 4. Conversion of Pyruvate to Acetyl CoA 5. Citric acid cycle 6. Gluconeogenesis pathway (pyruvate to glucose)
- Identify different types of organic reaction mechanims in the followingmetabolic pathways.1. Catabolism of triacylglycerols- beta-oxidation pathway2. Biosynthesis of fatty acids from Acetyl CoA3. Glycolysis (from glucose to two molecules of pyruvate)D. The following reactions are encountered in the metabolic cycles. Give the main class of enzymes that catalyzes these reactions. / 7. acetyl CoA + oxaloacetate citric acid 8. pyruvate + CO2 + ATP + oxaloacetate + ADP + P. 9. creatine + ATP phosphocreatine + ADP 10. alanine → propanoic acid + NH, 11. ala-gly-val → ala + gly + val 12. acetylcholine ester choline + acetic acid 13. triglyceride - 3 fatty acids + glycerol 14. deoxyribose + bases (A, G, C, T) + P, - DNA 15. glyceraldehyde-3-phosphate + dihydroxyacetone phosphateA. Identify different types of organic reaction mechanims in the following metabolic pathways.4. Conversion of Pyruvate to Acetyl CoA5.Citric acid cycle6. Gluconeogensis pathway (pyruvate to glucose) B. Identify at most 5 organic reactions for each metabolic pathway.
- A. What would happen in the Krebs cycle with the loss of activity of phosphoglycerate kinase? What would happen in glycolysis? 10. What happens to glycolysis with the addition of high amounts of citrate? What happens to ETS? 11. What happens in the Krebs cycle with a block in fumerase? 12.If an amino acid enters the Krebs cycle at the acetyl CoA entry point, how much more ATP is being made than if it enters at a keto-glutarate?Identify different types of organic reaction mechanism (SN1, SN2, etc.) and reaction types (Addition, elimination, etc ) in the following metabolic pathways. 1. Conversion of Pyruvate to Acetyl CoA 2. Citric acid cycle 3. Gluconeogenesis pathway (pyruvate to glucose)Part A Identify each of the following metabolic pathways. Drag the appropriate labels to their respective targets. Reset Help the conversion of fatty acids to 2-carbon units of acetyl CoA ketogenesis the conversion of an amino acid to an a-keto transamination acid the combination of 2-carbon units of acetyl COA to form fatty acids oxidative deamination the removal of an amino group as NH4+ from B oxidation glutamate to yield a-ketoglutarate lipogenesis the production of ketone bodies
- Identify different types of organic reaction mechanims in the following metabolic pathways. Conversion of Pyruvate to Acetyl CoA Citric acid cycle Gluconeogenesis pathway (pyruvate to glucose) Catabolism of triacylglycerols- beta-oxidation pathway Biosynthesis of fatty acids from Acetyl CoA Glycolysis (from glucose to two molecules of pyruvate)B1. Complete the Kreb's Cycle Acetyl CoA Citric Acd Malate dehydrogenase NADH NAD Isocitrate NAD Isocitrate Fumarase dehydrogenase NADH Fumarate NAD" FAD COASH Succinate dehydrogenase Succinate Succinyl CoA Succinyl CoA synthetase B2. How many ATP molecules can be produced from 4 molecules of Acetyl CoA if all of them enter the Kreb's Cycle? Assume all the energy yielding products enters the electron transport chain.Select all of the following that accurately apply to acyl-CoA synthetase and the transport of acyl-CoA through the carnitine transport system in the liver: 00 ☐☐☐☐ Acyl-CoA is formed when CoA serves as a nucleophile for attack of the fatty acyl-adenylate intermediate Fatty acid carbon skeletons are simultaneously used in the liver for beta oxidation and glucose biosynthesis The carnitine transport system is inhibited in the presence of high amounts of malonyl CoA The carrier protein carnitine replaces CoA in the transport of fatty acyl groups across the inner- mitochondrial membrane and allows acyl-CoA reformation in the matrix Increased need for beta oxidation allows for decreased transport of fatty acids via the carnitine transport system The formation of acyl-CoA by acyl-CoA synthetase involves the use of 2 equivalents of ATP - (1) an ATP used for activation of fatty acyl-adenylate and (2) an equivalent of ATP in the form of pyrophosphate hydrolysis