Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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Cells that have deregulated expression of telomerase can become cancerous. This can be attributable to what?
A. Telomerase can directly induce mutations in essential genes that can result in cancer.
B. Telomerase allows cells to replicate indefinitely without end-shortening issues.
C. Telomerase interferes with the function of repair enzyme complexes at the ends of the chromosome, causing DNA damages to persist.
D. Telomerase inhibits regulators of the cell cycle leading to cancer.
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- Why are errors in DNA methylation so destructive to cells? a. They cause improper activation or inactivation of DNA segments coding for important genes or micro RNAs. b. They cause improper methylation of proteins. c. They cause improper methylation of mRNA transcripts. d. All of these are possible explanations for methylation error damage..arrow_forwardWhich of the following is true about the enzyme telomerase? A. It is found only in adult cells. B. It is responsible for telomere shortening. C. It can re-establish telomere length. D. It may speed up the aging process. E. It is expressed at low levels in cancer cells.arrow_forwardExplain each optionsarrow_forward
- Suppose you isolated a mutant strain of yeast that replicates its DNA more than once per cell cycle. In other words, each gene in the genome was replicated several times between successive cell divisions. How might you explain such a phenomenon?arrow_forwardWhen replication happens, how much of cell’s DNA will be replicated? Select one: a. All of it – all chromosomes in their entirety b. Only genes which are needed by that particular cell type c. Only genes which are being actively transcribed d. Only one member of each homologous pair of chromosomesarrow_forwardFor the Igf2 gene, where do de novo methylation and maintenancemethylation occur?a. De novo methylation occurs in sperm, and maintenancemethylation occurs in egg cells.b. De novo methylation occurs in egg cells, and maintenancemethylation occurs in sperm cells.c. De novo methylation occurs in sperm, and maintenancemethylation occurs in somatic cells of offspring.d. De novo methylation occurs in egg cells, and maintenancemethylation occurs in somatic cells of offspring.arrow_forward
- Q.Sheltrin protein complex that has the following function: a.Protect telomerase from damage b.Protect telomere from damage c.Proteins as chaperones in autophagy d.Responsible in Proteostasis Q.Telomeres shorten by 50-200 bases with every cell division due to. a.End replication problem b.Cellular senescence c.mutations of Sheltrin proteins d.DNA Recombinationarrow_forwardWhat is a recombinant DNA? Select one: a. During meiosis, sister chromatids cross over to produce daughter cells with recombinant DNA. b. Any genome that is non-parental is called a recombinant DNA. c. New DNA sequences are inserted into a genome to produce recombinant DNA. d. Bacterial plasmid with sticky ends are referred to as the recombinant DNA.arrow_forwardIn eukaryotes, chromatin remodeling plays an important role is gene regulation. This is because a. repositioning of the nucleosomes makes DNA accessible to transcription regulatory proteins b. the nucleosomes contain important regulatory regions c. chromatin remodeling activates gene expression d. chromatin remodeling represses gene expressionarrow_forward
- The more cells divide, the more likely it is that mutationswill accumulate in their genomes. Explain how ?arrow_forwardWhy would a scientist wish to induce mutations? a. to increase the number of mutated phenotypes b. to create mutations in specific genes c. to test for carcinogen activity d. to create tumors for cancer research e. because she was crazier than a mutated bedbugarrow_forwardHow is the "language" of a molecule made of nucleotides converted into a molecule made of amino acids? O a. Using the process of meiosis, according to the semi-conservative synthesis model O b. Using the process of replication, according to complementary base pairing O c. Using the process of transcription, according to complementary base pairing d. Using the process of translation, according to the genetic codearrow_forward
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