Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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- Explain why a heteroduplex region may be produced after branch migration occurs.arrow_forwardThe diagram shown represents the coding strand of the myosin gene. Mutations in myosin can lead to muscle defects during development. Using what you know about how mutations can affect transcriptional and post-transcriptional regulation, match the results shown on the Northern (mature mRNA) to the mutations shown. The N lane shows the size and amount expected for non-mutated myosin mRNA. All samples were loaded at the top (-) side of the gel. Part 1. Which lane or lanes on the gel could be the result of mutation A? --4 ТАТАА AUG UAA Only known regulatory region TSS Mutation B: Mutation C. A: 5-base 20 nucleotides 3 nucleotides deletion deleted changed N 1 2 3 4 5arrow_forwardIn eukaryotes, chromatin remodeling plays an important role is gene regulation. This is because a. repositioning of the nucleosomes makes DNA accessible to transcription regulatory proteins b. the nucleosomes contain important regulatory regions c. chromatin remodeling activates gene expression d. chromatin remodeling represses gene expressionarrow_forward
- Describe how methylation and acetylation of the histones changes gene expression in eukaryotes. What groups are added? How do these processes physically affect chromatin structure? Silencing or Enhancing expression?arrow_forwardIf an organism's cells were to not want a specific sequence of DNA transcribed for a long period of time, which of the following processes below would most likely allow for this to happen? O DNA acetylation O DNA methylation O histone methylation O histone acetylationarrow_forwardThe diagram shown represents the coding strand of the myosin gene. Mutations in myosin can lead to muscle defects during development. Using what you know about how mutations can affect transcriptional and post-transcriptional regulation, match the results shown on the Northern (mature mRNA) to the mutations shown. The N lane shows the size and amount expected for non-mutated myosin mRNA. All samples were loaded at the top (-) side of the gel. Part 1. Which lane or lanes on the gel could be the result of mutation A? ТАТА AUG UAA Only known regulatory region TSS Mutation B: Mutation C. 3 nucleotides 20 nucleotides deleted A: 5-base deletion changed 1 2 4 5 lane 1 lane 2 lane 3 lane 4 lane 5 OOO0Oarrow_forward
- Which of the following mutations in the protein-coding region of a gene is more likely to lead to complete loss of function of the encoded protein: an insertion of six nucleotides or a deletion of two nucleotides? Briefly explain your answer.arrow_forwardIn skin cells, a gene is never transcribed. Give two ways this could occur.arrow_forwardHow would each of the following types of mutations affect proteinfunction or the amount of functional protein that is expressed froma gene?A. Nonsense mutationB. Missense mutationC. Up promoter mutationD. Mutation that affects splicingarrow_forward
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