Briefly explain why beta turns are found at the surface of proteins rather than in their hydrphobic core

What is the pelleting time for eukaryotic ribosome subunits, 40S and 60S, in a rotor with k = 180? Assume that the medium viscosity and density are similar to water at %3D 20°C.

VI. Although most biologically relevant sugars have the D-configuration, L-fucose is a commonly observed monosaccharide component in glycoproteins. Glycosylated antibodies (IgGs) observed in patients with active TB have more fucose than those found in patients with latent TB (Lu et. al., 2016). Latent TB occurs when a person has the TB bacteria, but bacterial proliferation is kept under control by the body's immune system; hence, the infected person is asymptomatic and not infectious. A person with latent TB will test positive for the tuberculin test or TB blood test. a) L-fucose is also known as 6-deoxy-L-galactose. Note that D-galactose is a C-4 epimer of D-glucose. Draw the Fisher projections for D-glucose, D-galactose and L-fucose. (Hints: D- and L-isomers are enantiomers. 6-deoxy means that the hydroxyl group at C-6 is removed leaving just the methyl group). D-galactose: D-glucose: L-fucose (6-deoxy-L-galactose): b) L-fucose can cyclize into a pyranose and form two anomers. Draw…

cip sequence rule in ephedrine

Only answer please, no need to explain… Thank you for your time. i:  Modification of the 5 prime ends of eukaryotic mRNA is called? a) Capping b) Polyadenylation c) Splicing d) Transcription ii: Genetic Code is? a) The sequence of Nitrogenous Bases in mRNA that codes for a protein b) Is a Triplet Code      c) is Non-Overlapping      d) All of these iii. The process of formation of RNA is known as a) Replication          b) DNA repair         c) Translation           d) Transcription iv. Which of the following statement is NOT true regarding transcription/RNA synthesis? a) RNA synthesis occurs in the nucleus b) Unlike DNA synthesis, the only selective sequence of DNA is transcribed to RNA   c) RNA synthesis requires a short stretch of RNA primers d) DNA sequences, specific proteins, and small RNAs regulate RNA synthesis

a. Suppose that you have the peptide Ala-Gly-Tyr-His-Leu and you treat it with FDNB and then 6M HCl. Draw the structures of all the products that you will have in solution (assume all reactions to go to completion).

Liposomes used in these vaccines contain some cationic lipids, or lipids with a positively charged head group.  Explain why this is a sensible strategy for delivering genetic materials (or drugs) to a human cell.

Small molecules are used as inhibitors of protein action - as drugs. They most often do this by blocking the active site within the protein. Potential drugs can be screened computationally to determine if they are strongly bound to the protein. Figure 1 shows a possible conformation of a candidate drug molecule, 4-bromo-2- carboxymethylamide-pyrrole (abbreviation: BCMAP) at the active site of a protein (abbreviation: PR). Figure 2 shows the full protein structure whilst figure 3 shows a known inhibitor of the protein at the site, overlayed with another calculated conformer of BCMAP. (a) Explain what types of interactions, both intermolecular and intramolecular, that a molecular mechanics forcefield must be able to describe in order to be able to accurately determine the geometry of BCMAP in the protein. Identify which interactions will be the most important to describe accurately. Figure 1.4-bromo-2-carboxymethylamide-pyrrole (BCMAP) (C, N, O, and Br atoms in yellow, blue, red, and…

A cytosine is deaminated. Describe the outcome of this deamination and explain in detail how E. coli repairs this mutation using base excision repair (BER). This repair should contain 5 steps and describe the function of all enzymes or structures.

Hi, please help with this question: What is the net charge on the amino acid cysteine at pH 8.0? (pKa values are α-carboxyl 2; α-amino 10; side chain 8) Thanks