Answer for each 1, 2, 3, 4 and 5 labelled in the attached image: a)What is this molecule? b)What superfamily does it belong to? c)Which number points to the peptide binding domain?

4. You're working on a structure of a protein and its folding. You think that the interaction between Asp123 and Arg29 is important in determining the structure of the protein. a) What type of amino acid is Asp (acidic, basic, hydrophobic, or polar)? b) What type of amino acid is Arg (acidic, basic, hydrophobic, or polar)? c) What is the strongest interaction that can form between Asp123 and Arg29? You create a mutant Arg29> Lys d) What type of amino acid is Lys (acidic, basic, hydrophobic, or polar)? e) Would you expect this substitution mutation to cause major folding problems? Why or why not? You create mutant Arg29> Glu you discover that this mutant is unable to fold properly, so the protein is nonfunctional. f What type of amino acid is Glu (acidic, basic, hydrophobic, or polar)? g) How does this amino acid substitution cause the protein to fold incorrectly? You find another mutant that also as the same Arg29> Glu mutation. However, this mutant protein įs able to fold normally.…

Let’s suppose we have downloaded the structure of Hemoglobin from PDB. Now we want to retrieve the location of helices and loops in it. How can we do it? How can we depict a protein’s coordinate info in a modeling program? (Subject: Bioinformatics)

In standard nomenclature, peptide sequences are read out in which direction? a) C to N b) 3’ to 5’ c) N to C d) 5’ to 3’

Why must mRNAs contain the nucleotides AUG?Question 37 options: A) to bind the Shine-Dalgarno sequence B) to specify the reading frame C) to incorporate Phenylalanine into the protein D) to stop translation E) both A and B are correct

The nuclear import of proteins larger than 40 kDa requires the presence of what amino acid sequence? Describe the mechanism of nuclear import. How are nuclear transport receptors able to get through the nuclear pore complex?

A researcher has synthesized two peptides and needs to confirm whether the peptides were synthesized with the correct sequence using mass spectrometry. What is the sequence of the b4 and y7 ions for peptide GAMECHANGER?  The peptide SLISRAEFLAGVRVGV is digested with trypsin. Then the products of the digestion are subjected to ESI TOF-MS in positive ion mode with the peptides in a pH 2 solution. What peptide fragments will result and what are their m/z?

3)Which of the following statements are true? Choose all that apply a)There are multiple codons possible for nearly all amino acids b)Each stop codon also codes for an amino acid c)Each tRNA will base pair with only one codon d)The start codon also codes for an amino acid e)Each codon in mRNA codes for exactly one amino acid f)Each codon in tRNA codes for exactly one amino acid g)Each anticodon in tRNA pairs with exactly one codon h)Each tRNA carries exactly one type of amino acid

What protein structure is represented in either panel of the figure above?   Question 11 options:   a)  Quaternary   b)  Secondary   c)  Tertiary   d)  Quinary   e)  Primary