Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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- Antibodies Select one: a. are not specific, but act generally. b. are composed of four light and four heavy polypeptide chains. c. play a large role in cell-mediated immunity. d. are produced by both T and B cells. e. have a variable region that binds to a specific antigenic determinant.arrow_forwardDendritic cells take up, process or present antigen by all of the following routes except Select one: a. receptor-mediated endocytosis of bacteria. b. macropinocytosis of bacteria or viruses. c. uptake of viruses using Toll-like receptor TLR9. d. cross-presentation from the MHC class II pathway to the MHC class I pathway. Oe. cross-presentation from incoming infected dendritic cells to healthy resident dendritic cells in secondary lymphoid tissue. Of. delivery of viral peptides from cytosol to endoplasmic reticulum during viral infection.arrow_forwardSomatic cells can display antigen [small peptides] and present them to the body’s immunesystem via their MHC/HLA receptor displays. Discuss the paths for MHC/HLA1 vs. MHC/HLA2display. How do these two paths fit into the health of the body, and the response of theimmune system to normal/disease/infection?arrow_forward
- Identify which of the following statements regarding naive T cells is incorrect. a. Naive T cells have the capacity to survive for many years as nondividing circulating cells in the absence of specific antigen. b. Naive T cells express LFA-1 molecules that change their conformation after encountering a specific peptide:MHC complex. c. Naive T cells exit from lymph nodes using the same route as effector T cells. d. Naive T cells express ICAM-3, which binds to DC-SIGN on dendritic cells with high affinity. e. Naive T cells express high levels of S1P receptors on their surface.arrow_forwardA. Organism that causes diseaseB. Larger in children than adults, this organ is the site of T cell maturation.C. Small region of substance or organism that binds directly to antibody.D. With granules that take up acidic stains, these white blood cells defend against parasites.E. Star-shaped cells critical for T-cell activationF. One type of complement pathwayG. These molecules "show off' self or non-self-peptides to T cells.H. A protein fragment that tags cells for destruction by phagocytesI.Substance or organism that induces an immune response.I.May be released into circulation or serve as a B cell receptor.K. Signalling molecule made by virally infected cells.L. The most abundant white cells in the blood, these phagocytic cells have multilobed nucleiM. A laboratory procedure that can test for antigen or antibody.N. A remarkable intracellular complex that amplifies the innate immune responseO. Receptors that recognize pathogen products and cause macrophages to produceinterleukins.P. A…arrow_forward(i) Explain the role of Ras.GTP and Rac.GTP in the formation of active AP-1 during T- cell activation. (ii) Cadmium ions have been shown to be selective blockers of membrane calcium channels. Suppose T lymphocytes are cultured in the presence of cadmium chloride, explain what happens to TCR-triggered signal transduction.arrow_forward
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