
Please explain what cerebral spinal fluid (CSF) is, how it is made (structures involved); and discuss its complete circulation.
EXPLANATION ADDRESSING THE QUESTION ABOVE
Cerebral spinal fluid is a fluid that cushions the central nervous system and provides buoyancy to and helps nourish the brain. It circulates around the surface of the brain, interior ventricles, and surface of the spinal cord and central canal of the spinal cord. CSF is created by the ependymal cells in the choroid plexus and ventricles of the brain. CSF is made up mostly of water and also includes ions, nutrients like vitamin c and protein, and can pick up waste as it circulates. CSF circulation starts in the lateral ventricle where the choroid plexus and lateral ventricle creates or secretes the CSF. The CSF then flows through the ventricular foramen into the third ventricle. At the third ventricle, the CSF then flows through the cerebral aqueduct into the fourth ventricle. Then, the CSF exits the fourth ventricle through the lateral and medial apertures into the subarachnoid space and this is where the CSF washes over the brain and spinal cord. When the CSF exits the fourth ventricle, it also runs through the center of the spinal cord through the central canal of the spinal cord. Once the CSF reaches the subarachnoid space and is washing over the brain and spinal cord, it’s going to exit through the arachnoid villus which will allow the CSF to drain into the dural sinuses. The dural sinuses will carry the CSF and the waste that has been picked up along the way and will be dumped into the veins and the CSF that is dirty will be returned to the blood circulation so the waste can be disposed of.
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