Acety1 CoA Oxaloncetate CoA NADH Citrate NAD Isocitrate Malate Fuiarate NAD NADH FADH, FAD a-Ketoglutarate Succinate co, NAD ATP Succinyl CuA NADH ADP - P, For each molecule of glucose (C6H12O6) oxidized by cellular respiration, how many moles of CO2 are released in the citric acid cycle? (see the figure above) а. 2 b. 4 с. 6 d. O е. 3

Human Anatomy & Physiology (11th Edition)
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Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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**Transcription and Explanation for Educational Website:**

**Diagram Explanation:**  
The diagram illustrates the Citric Acid Cycle, also known as the Krebs Cycle, which is a key metabolic pathway that oxidizes Acetyl CoA to produce energy in the form of ATP. Significant intermediates and processes in the cycle include:

- Initiation with Acetyl CoA combining with Oxaloacetate to form Citrate.
- Sequential transformation into Isocitrate, then α-Ketoglutarate, and Succinyl CoA.
- Release of CO₂ molecules during the transformation from Isocitrate to α-Ketoglutarate and from α-Ketoglutarate to Succinyl CoA.
- Regeneration of Oxaloacetate from Malate.
- Energy carrier molecules NADH, FADH₂, and ATP are produced throughout the cycle.

**Question:**  
"For each molecule of glucose (C₆H₁₂O₆) oxidized by cellular respiration, how many moles of CO₂ are released in the citric acid cycle? (see the figure above)"

**Options:**  
a. 2  
b. 4  
c. 6  
d. 0  
e. 3

---

The correct answer involves considering the cycle's operation per glucose molecule, as each glucose results in two turns of the citric acid cycle.
Transcribed Image Text:**Transcription and Explanation for Educational Website:** **Diagram Explanation:** The diagram illustrates the Citric Acid Cycle, also known as the Krebs Cycle, which is a key metabolic pathway that oxidizes Acetyl CoA to produce energy in the form of ATP. Significant intermediates and processes in the cycle include: - Initiation with Acetyl CoA combining with Oxaloacetate to form Citrate. - Sequential transformation into Isocitrate, then α-Ketoglutarate, and Succinyl CoA. - Release of CO₂ molecules during the transformation from Isocitrate to α-Ketoglutarate and from α-Ketoglutarate to Succinyl CoA. - Regeneration of Oxaloacetate from Malate. - Energy carrier molecules NADH, FADH₂, and ATP are produced throughout the cycle. **Question:** "For each molecule of glucose (C₆H₁₂O₆) oxidized by cellular respiration, how many moles of CO₂ are released in the citric acid cycle? (see the figure above)" **Options:** a. 2 b. 4 c. 6 d. 0 e. 3 --- The correct answer involves considering the cycle's operation per glucose molecule, as each glucose results in two turns of the citric acid cycle.
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