a) What is the role of the Hox genes in animal development and what types of phenotypes do you see in mutations of Hox genes?Provide an example of a mutant phenotype of a Hox gene in Drosophila. 3mrksThe Hox genes are known to act in combination. Panel A in figure below shows the normal expression patterns of the bithoraxcomplex, and segments that align with the expression patterns. Panel B shows the segmental phenotypes in mutants for bothabdominal - A and Abdominal - B, panel C shows the phenotypes in mutants for Abdominal - B, and panel D shows the phenotypesin mutants for Ultrabithorax.b) Describe how the segmental phenotypes illustrate the combinatorial action of Hox genes (you can ignore A9 as it is patterned by theterminal patterning system). 4mrksA) Parasegments11 12 13 14B)D)10 11 12 13 14SegmentsA2 A3 A4 A5Abdominal-Babdominal-AUltrabithoraxT1 12 13 A111 12 12 12 A2 A3 A4 A

a) Role of Hox Genes in Animal Development and Mutant PhenotypesHox genes are a group of genes that…

Answered: a) What is the role of the Hox genes in…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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You inject bicoid MRNA into the posterior end of a fertilized fruit fly egg just prior to the first cleavage. How will the experiment affect Hox gene expression in this fly? How will it affect the fly embryo's anatomy? Explain your answer, demonstrating your understanding of the role bicoid and Hox genes play in development.
Discuss the morphological differences between the parasegments and segments of Drosophila. Discuss the evidence, providing specific examples, that suggests the parasegments of the embryo are the subdivisions for the organization of gene expression.
which Nodal gene expression is activated in the left side of the body differs among the vertebrate classes.
Molecular geneticists have performed experiments in which they altered the number of copies of the bicoid gene in flies, affecting the amount of Bicoid protein produced. a. What would be the effect on development of an increased number of copies of the bicoid gene? b. What would be the effect of a decreased number of copies of bicoid? Justify your answers.
Person A express a gene can regulate the expression of multiple language gene. What could be the probable protein/enzyme that the gene could code for? How could the enzyme regulate gene expression?
Please answer question 10
And see the following question correctly thanks
Molecular geneticists have performed experiments in which they altered the number of copies of the bicoid gene in flies, affecting the amount of Bicoid protein produced. Q. What would be the effect on development of an increased number of copies of the bicoid gene?
The figure below shows the distribution of proteins during embryo development in Drosophila. These proteins are encoded by which types of genes? Which proteins regulate the expression of these genes?
Developmental abnormalities can result from: 1. Under expression of some genes 2. All of these choices are correct 3. Inappropriate interaction among gene products that were expressed in the wrong amounts and wrong time 4. Over expression of some genes 5. corrupted timing of the normal time genes are expressed
Below are data from Jimenez et al (2022) depicting cellular expression patterns of the tumor suppressor transcription factor p53 (a gene commonly mutated in cancers). They explored oscillating expression patterns found in a mutated human cell line. Panel D shows measurements of changes in p53 mRNA levels measured using two different approaches; figure E shows measurements of protein levels from the same samples. The numbers on either side indicate the observed fold change (FC) in relative abundance of these molecules (note that any difference in values obtained between the two methods are not relevant for this question). Answer part b as pictured in the question

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