Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Question
a. A single mutation in the riboswitch’s sequence changes the ligand binding specificity from guanine to
adenine. Predict what single mutation could be made in the guanine-responsive riboswitch sequence
to convert it to an adenine-responsive riboswitch. Justify your answer
b. Could a DNA molecule with the same
guanine in a similar manner as the RNA-based molecule? Explain
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