A receptor, R, binds to its ligand, L, according to the binding curve shown below. If[R]= 30 mM at the KD, what is the concentration of the receptor-ligand complex atthe KD?1.0Q210 15 20 2530 35 40 45 50 55 600 0.540 mMO 25 mMO 30 mMO 10 mM17.5 ml5[Ligand] (mm) You are evaluating the kinetics of an enzyme catalyzed reaction containing 5.5 μM total enzyme and 11.2μM substrate. At this substrate concentration, you determine that theVo = 88.6 μmol mL-¹. s-¹. If the Vmax833.3 mM s the KM is:.=="30.9 μΜ10.4 μΜΟ 124.6 μΜ234 μΜ94.5 μM

Kd is dissociation constant which is ligand concentration at half of the saturation of receptors or…

Answered: A receptor, R, binds to its ligand, L,…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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In your acid phosphatase enzyme kinetics lab, you constructed a Lineweaver-Burk plot. Lefs assume that you graphicaly obtain 1/Vmax - 9.33 (umoliey and -1Km--0.012 M. Which of the following is correct? A) Vmax = 9.33 (no units) B) Km = 0.012 (no units) C) Vmax = (1/Vru" = 0.107 umolis D) Km =-14-1K = 83.3 pM E) Both C) and D) are correct
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A receptor, R, binds to its ligand, L, according to the binding curve shown below. If [R]= 30 mM at the KD, what is the concentration of the receptor-ligand complex at the KD? 1.0 Q2 10 15 20 25 30 35 40 45 50 55 60 0 0.5 40 mM O 25 mM O 30 mM O 10 mM 17.5 ml 5 [Ligand] (mm)