A molecular researcher, Dr. Sidra Alkatini, is investigating the manifestation of a disorder in some of her lab mice models, which are lacking production of an important protein necessary for the cellular respiration pathway. The afflicted mice are short lived, and have perpetually low blood glucose levels, no matter how much food they are fed. Through sequencing, the following strand of DNA was produced: 5’ TTC CAA TTA CGC CGC TAT ACG CGC ACC ATG TTA TCA TGT TGG TGG TAG 3’ Given your expertise in genetics, she contacts you, her BFF, to help her understand the sequence and its relation to the genetic disorder she is seeing. 1) Considering the entire DNA sequence shown above, specify the numbered codon that represents START. a Codon 10. b Codons 12-13. c Codon 9. d Codons 28-30. 2) Indicate three motifs that justify this as being a eukaryotic sequence. a CAAT, TATA, ACCATGG. b GACA, TATAAT, AAUAA. c TTAC, ATG, TGA. d TAA, TGA, and TAG.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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molecular researcher, Dr. Sidra Alkatini, is investigating the manifestation of a disorder in some of her lab mice models, which are lacking production of an important protein necessary for the cellular respiration pathway. The afflicted mice are short lived, and have perpetually low blood glucose levels, no matter how much food they are fed. Through sequencing, the following strand of DNA was produced:

                   5’ TTC CAA TTA CGC CGC TAT ACG CGC ACC ATG TTA TCA TGT TGG TGG TAG 3’

Given your expertise in genetics, she contacts you, her BFF, to help her understand the sequence and its relation to the genetic disorder she is seeing.

 
1) 
Considering  the entire DNA sequence shown above, specify the numbered codon that represents START.
 
a
Codon 10.
b
Codons 12-13.
c
Codon 9.
d
Codons 28-30.
 
2) 
Indicate three motifs that justify this as being a eukaryotic sequence.
 
a
CAAT, TATA, ACCATGG.
b
 GACA, TATAAT, AAUAA.
c
TTAC, ATG, TGA.
d
TAA, TGA, and TAG.
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