9) In another mutation from the original wild-type sequence, the bolded G in the middle of the second line is mutated to A. A)How many amino acids are in the protein encoded by the MRNA? amino acids B) Using a codon chart (posted under the Translation module in Moodle), translate the mRNA transcript with the mutation described in 9 into protein, using the single letter amino acid code and no spaces. N terminus- -C terminus

Human Anatomy & Physiology (11th Edition)
11th Edition
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Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Use the first picture and codon table to answer the following questions.

A. Below is a small 2 exon long gene. The exons are underlined, and the 22 nucleotide long intron is the non-
underlined sequence between the exons. TAG, TAA, and TGA are stop codons.
5'-TAGTGTATTGACATGATAGAAGCACTCACTATATTCTGACGTGCGACTATGCGTGGGGTTAGGT
ATTGTGCTGACTTTTCTCAGGTGGCCCGTATAGGCTAAGCTGCGCATCGCCGCTAGTCGCTCAGTTCCGC
TGGCGGCATTTTAACTTTCTTTAATGAATGCGGGCATATTTAATACGCGCTATGCGCATCGTATGCGAT-3'
Transcribed Image Text:A. Below is a small 2 exon long gene. The exons are underlined, and the 22 nucleotide long intron is the non- underlined sequence between the exons. TAG, TAA, and TGA are stop codons. 5'-TAGTGTATTGACATGATAGAAGCACTCACTATATTCTGACGTGCGACTATGCGTGGGGTTAGGT ATTGTGCTGACTTTTCTCAGGTGGCCCGTATAGGCTAAGCTGCGCATCGCCGCTAGTCGCTCAGTTCCGC TGGCGGCATTTTAACTTTCTTTAATGAATGCGGGCATATTTAATACGCGCTATGCGCATCGTATGCGAT-3'
|
Second base of codon
U
A
UAU
UUU
Phenylalanine
UUC
UCU
UGU
Tyrosine
tyr y
Cysteine
cys C
phe F
UCC
UAC
UGC
C
Serine
ser s
U
UUA
UGA STOP codon
UAA
STOP codon
UAG
Leucine
UCA
A
UGG Tryptonphan
trp"
UUG
leu
UCG
CUU
CCU
CAU
CGU
U
Histidine
his
C
CUC
Leucine
CCC
Proline
CAC
H
CGC
Arginine
CỦA
leu L
ССА
pro P
СА
Glutamine
CGA
arg
R
CUG
CCG
CAG
gin
CG
AUU
ACU
AAU
AGU
Asparagine
asn N
Serine
Isoleucine
A
AUC
ACC
Threonine
AAC
AGC
ser s
ile |
AUA
АСА
thr T
AAA
AGA
A
Lysine
Methionine M ACG|
AUG met (start codon)*
Arginine
arg R
AAG
AGG
lys
K.
GUU
GCU
GAU
Aspartic acid
GAC
GGU
U
GUC
G
GCC
Alanine
asp D
GGC
C
Glycine
gly
Valine
GUA
val V
GCA
ala
А
GAA
Glutamic acid
GGA
G
A
GUG
GCG
GAG
glu E
GGG
9) In another mutation from the original wild-type sequence, the bolded G in the middle of the second
line is mutated to A.
A)How many amino acids are in the protein encoded by the mRNA?
amino acids
B) Using a codon chart (posted under the Translation module in Moodle), translate the mRNA
transcript with the mutation described in 9 into protein, using the single letter amino acid code
and no spaces.
N terminus-
-C terminus
Third base of codon
First base of codon
Transcribed Image Text:| Second base of codon U A UAU UUU Phenylalanine UUC UCU UGU Tyrosine tyr y Cysteine cys C phe F UCC UAC UGC C Serine ser s U UUA UGA STOP codon UAA STOP codon UAG Leucine UCA A UGG Tryptonphan trp" UUG leu UCG CUU CCU CAU CGU U Histidine his C CUC Leucine CCC Proline CAC H CGC Arginine CỦA leu L ССА pro P СА Glutamine CGA arg R CUG CCG CAG gin CG AUU ACU AAU AGU Asparagine asn N Serine Isoleucine A AUC ACC Threonine AAC AGC ser s ile | AUA АСА thr T AAA AGA A Lysine Methionine M ACG| AUG met (start codon)* Arginine arg R AAG AGG lys K. GUU GCU GAU Aspartic acid GAC GGU U GUC G GCC Alanine asp D GGC C Glycine gly Valine GUA val V GCA ala А GAA Glutamic acid GGA G A GUG GCG GAG glu E GGG 9) In another mutation from the original wild-type sequence, the bolded G in the middle of the second line is mutated to A. A)How many amino acids are in the protein encoded by the mRNA? amino acids B) Using a codon chart (posted under the Translation module in Moodle), translate the mRNA transcript with the mutation described in 9 into protein, using the single letter amino acid code and no spaces. N terminus- -C terminus Third base of codon First base of codon
Expert Solution
Step 1

The DNA is transformed into proteins through the process of transcription and translation.  The process of transcription changes the DNA to mRNA and in the post-transcriptional process, the regions of introns that non coding regions get spliced, and the coding regions of exons are attached together. These coding regions are translated to the proteins through the process of translation.

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