7. Scientists studying the genetics of a congenital discase analyzed the chromosomes of the patient and found a large portion of chromosome twenty-three in 188 Chapter 3. Gene expression and protein synthesis chromosome one, and a small part of chromosome one in chromosome twenty- three. What type of mutation is this? To answer the question, please explain: 1) what the mutation is? 2) what types of mutation do you know?

5b. When you mutagenize a diploid organism, chances are astronomically high that you will be creating a heterozygote on the spot. Why would your mutation be heterozygous and not homozygous?

Part 1: Matching Match the term with its corresponding definition.   a. Insertion e. Nonsense Mutation b. Deletion f. Missense Mutation c. Frameshift Mutation g. Germ-line Cells d. Silent Mutation h. Somatic Cells     ____       1.            Remove a base or bases   ____       2.            Add a base or bases   ____       3.            Mutations in these cells are not passed to future generations but are passed to other body cells derived from them   ____       4.            Mutation in which an amino acid is changed to a stop codon and the protein is truncated   ____       5.            Mutations in these cells are passed to future generations   ____       6.            Results if an insertion or deletion throws the reading frame of the gene message out of register   ____       7.            Mutation where the protein does not change   ____       8.            Mutation where a codon is changed resulting in another amino acid inserted in…

1. Describe several different DNA repair mechanisms. Which ones contribute to mutations?   2. What is the difference between an ortholog and a paralog

22. With which protein(s) is a condensed eukaryotic chromosome NOT known to be associated? 1. core histones H2A, H2B, H3, and H4   2.histone H1   3.SMC proteins   4.topoisomerase I   5.topoisomerase II

23. The location of a specific gene on a chromosome is called? A. The gene position B. The gene location C. The gene pocus D. The gene locus