7. A 35-year-old villager with IDDM was examined in the hospital and assured theendocrinologist that he has kept strictly to the recommended diet during insulintreatment. The screening showed that the blood glucose concentration was6.2 mmol/L; HbA, level was 11.7% (norm 4-6%); no glucose or ketone bodieswere detected in the urine. After reviewing the results of laboratory studies,the attending physician was in doubt that the patient followed his nutritionalguidelines. Explain this doctor's query. For answer:a) name the reason for the blood HbA, increase;b) list the late complications of diabetes mellitus and explain the molecularmechanisms of their occurrence.

Insulin is the peptide hormone produced by the beta-cells of islets of Langerhans of the pancreas.…

Answered: 7. A 35-year-old villager with IDDM was…

Essentials of Pharmacology for Health Professions

7th Edition

ISBN:9781305441620

Author:WOODROW

Publisher:WOODROW

ChapterCRE2: Comprehensive Review Exam For Part 2

Section: Chapter Questions

Problem 47CEP2

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4. (a) If a 10-mL vial of insulin contains 100 units of insulin per milliliter, and a pa- tient is to administer 20 units daily, how many days will the product last the pa- ра- tient? (b) If the patient returned to the pharmacy in exactly 7 weeks for another vial of insulin, was the patient compliant as indicated by the percent compliance rate? 5. A prescription is to be taken as follows: 1 tablet q.i.d. the first day; 1 tablet t.i.d. the second day; 1 tablet b.id. X 5 d; and 1 tablet q.d. thereafter. How many tablets should be dispensed to equal a 30-day supply?
A 30yrs old pregnant woman who was distressed was presented to the Antenatal Clinic with an unexplained weight loss, dehydrated secondary to polyuria, nausea, vomiting, hypotension and tachycardia. You further requested for Modified Oral Glucose Tolerance Test. The OGTT results came as follows; After overnight fast, FBS- 3.9 mmol/L Reference (
A 30yrs old pregnant woman who was distressed was presented to the Antenatal Clinic with an unexplained weight loss, dehydrated secondary to polyuria, nausea, vomiting, hypotension and tachycardia. You further requested for Modified Oral Glucose Tolerance Test. The OGTT results came as follows;After overnight fast, FBS- 3.9 mmol/L Reference (</= 5.3mmol/L)After an hour of oral glucose RBS- 11mmol/L Reference (</= 10.0mmol/L)After 2hours RBS- 9.6mmol/L Reference (</= 8.6mmol/L)After 3hours 8.8mmol/L Reference (</= 7.8 mmol/L) What will be your clinical diagnosis? How is the execution and the interpretation of Modified Glucose Tolerance Test? What are the Biomedical reasons for the modification in (B) Above? Outline the procedure for Modified OGTT What will be the treatment option for the patient? What other laboratory test apart from FBS/RBS can you request to monitor treatment?
1. Explain why Benedict’s test is useful for diagnosis of diabetes using urine sample?
A patient attending an obesity clinic is found to have ketonuria on urinalysis. There is no glycosuria and points-of-care glucose measurement using a strip is 5.9 mol/L. What might explain these findings?
1. What are the possible indications if there is a presence of protein in a patient's urine sample?2. What are the possible indications if there is a presence of glucose in a patient's urine sample?
15. Your pharmacy has on hand NPH Insulin 100 units/mL.You receive a prescription for NPH Insulin and the patient is to inject subq 32 units qam. How many milliliters of insulin does the patient need to inject to receive the 32 units?
The glucose tolerance test is prescribed under which of the following patient scenarios? Ⓒ Fasting blood sugar greater than 7.8 mmol/L and patient presents with the signs and symptoms of hyperglycemia. Fasting blood sugar greater than 7.8 mmol/L Fasting blood sugar increased and patient asymptomatic. Fasting blood sugar less than 7.8 mmol/L and patient presents with the signs and symptoms of hyperglycemia
1. Explain the procedure for 2 hour post prandial testing and oral glucose tolerance testing . Give the reference values
43. A 13 year old boy with type 1 diabetes mellitus is brought to the emergency department because of nausea and weakness for 24 hours. He did not take his last 3 doses of insulin. His temperature is 37C(98.6F), pulse is 120/min, respirations are 30/min, and blood pressure is 90/60 mm Hg. Physical examination shows dry mucous membranes and decreased skin turgor. Laboratory studies show: Serum HCO3 Glucose Arterial blood gas analysis on room air: pH PCO2 6 mEq/L 400 mg/dL a. Buffering by HCO3 b. Buffering by inorganic phosphates c. Buffering by intracellular proteins d. Increased renal excretion of titratable acid e. Pulmonary excretion of CO2 derived from HCO3 7.10 20 mm Hg Which of the following processes is the initial defense against the decrease in arterial pH in this patient?
The giucose tolerance test is prescribed under which of the following patient scenarios? Fasting blood sugar greater than 7.8 mmol/L and patient presents with the signs and symptoms of hyperglycemia. Fasting blood sugar greater than 7.8 mmol/L O Fasting blood sugar increased and patient asymptomatic. Fasting blood sugar less than 7.8 mmol/L and patient presents with the signs and symptoms of hyperglycemia
A laboratory result Shows a glucose level 10.1mg/dl ( reference range 3 - 6.2mg/dl) BP of 140/100 mmHg ( Reference 120/80 mmHg) Serum insulin 0.3 ( 0.7-3.5) BMI is 34kg/m sq Other findings seen was porous bone, muscle weakness and stretch marks, high appetite hyperpigmentation of the skin. Moon face, truncal abdomen.etc a. As a Medical laboratory scientist, use the laboratory results ( hint explain each findings) and the other findings to diagnose the disorder. b. What 2 causes of it

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