Biochemistry
Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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NH, NH," 'N NH tRNA specific adenosine deaminase Adenine Inosine RNA tRNA 3rd attempt ai See Periodic Table The figure provided in in the introduction above shows adenine being deaminated to form the noncanonical nucleotide inosine. Noncanonical base pairings between TRNA and MRNA occur frequently and helped lead to the wobble hypothesis concerning the relaxed base pairing rule for the third position of an MRNA codon. With respect to adenine and inosine shown in the figure, which of the following is false? Choose one: A The hydrogen-bond donor on inosine (in the orange box) is likely to form a weaker hydrogen bond than will the hydrogen-bond donor on adenine (in the orange box) if distance and orientation are optimized for both. O B. The functional group in the square orange box in adenine can serve as both a hydrogen-bond donor and a hydrogen-bond acceptor. C. The enzyme responsible for this reaction works on TRNA, and not on MRNA. O D. The inosine on a tRNA can base-pair with adenine, cytosine, or uracil on MRNA if that MRNA nucleotide is in the third codon position, the "wobble" position. orur
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Transcribed Image Text:NH, NH," 'N NH tRNA specific adenosine deaminase Adenine Inosine RNA tRNA 3rd attempt ai See Periodic Table The figure provided in in the introduction above shows adenine being deaminated to form the noncanonical nucleotide inosine. Noncanonical base pairings between TRNA and MRNA occur frequently and helped lead to the wobble hypothesis concerning the relaxed base pairing rule for the third position of an MRNA codon. With respect to adenine and inosine shown in the figure, which of the following is false? Choose one: A The hydrogen-bond donor on inosine (in the orange box) is likely to form a weaker hydrogen bond than will the hydrogen-bond donor on adenine (in the orange box) if distance and orientation are optimized for both. O B. The functional group in the square orange box in adenine can serve as both a hydrogen-bond donor and a hydrogen-bond acceptor. C. The enzyme responsible for this reaction works on TRNA, and not on MRNA. O D. The inosine on a tRNA can base-pair with adenine, cytosine, or uracil on MRNA if that MRNA nucleotide is in the third codon position, the "wobble" position. orur
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