2 um DNA strand Scaffold (a) Metaphase chromosome (b) Metaphase chromosome treated with high salt to remove histone proteins FIGURE 10.18 The importance of histone proteins and scaffolding proteins in the compaction of eukaryotic chromosomes. (a) A metaphase chromosome. (b) A metaphase chromosome following treatment with highly concentrated salt solution to remove the histone proteins. The black arrow on the right points to an elongated strand of DNA. The white arrow on the left points to the scaffold (composed of nonhistone proteins), which anchors the bases of the radial loops. As shown earlier in Figure 10.17d, this scaffold consists of protein filaments.

2 um DNA strand Scaffold (a) Metaphase chromosome (b) Metaphase chromosome treated with high salt to remove histone proteins FIGURE 10.18 The importance of histone proteins and scaffolding proteins in the compaction of eukaryotic chromosomes. (a) A metaphase chromosome. (b) A metaphase chromosome following treatment with highly concentrated salt solution to remove the histone proteins. The black arrow on the right points to an elongated strand of DNA. The white arrow on the left points to the scaffold (composed of nonhistone proteins), which anchors the bases of the radial loops. As shown earlier in Figure 10.17d, this scaffold consists of protein filaments.

Name: Consider how histone proteins bind to DNA and then explain whya high s
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Description: Consider how histone proteins bind to DNA and then explain whya high salt concentration can remove histones from DNA (asshown in 10.18b). 2 umDNA strandScaffold(a) Metaphase chromosome(b) Metaphase chromosome treated with high salt to remove histone

Biology: The Dynamic Science (MindTap Course List)

4th Edition

ISBN:9781305389892

Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Chapter14: Dna Structure And Replication

Section: Chapter Questions

Problem 11TYK: Discuss Concepts Eukaryotic chromosomes can be labeled by exposing cells to radioactive thymidine...

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Protein complex present at centromeres in mitotic cells structure formed when DNA wraps around an octameric histone core Protein complex that is degraded at anaphase to allow sister chromatids to separate at mitosis microtubule based structure used to segregate chromosomes in mitosis and meiosis 1. cohesin complex 2. kinetochore 3. monopolin 4. nucleosome 5. synaptonemal complex 6. telomere 7. sister chromatid 8. spindle
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Discuss Concepts Eukaryotic chromosomes can be labeled by exposing cells to radioactive thymidine during the S phase of interphase. If cells are exposed to radioactive thymidine during the S phase, would you expect both or only one of the sister chromatids of a duplicated chromosome to be labeled at metaphase of the following mitosis (see Section 10.2)?
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