Why is a chromosome with two centromeres (adicentric chromosome) unstable? Would a backup cen-tromere not be a good thing for a chromosome, giving ittwo chances to form a kinetochore and attach to microtu-bules during mitosis? Would that not help to ensure thatthe chromosome did not get left behind at mitosis?
Genetic Variation
Genetic variation refers to the variation in the genome sequences between individual organisms of a species. Individual differences or population differences can both be referred to as genetic variations. It is primarily caused by mutation, but other factors such as genetic drift and sexual reproduction also play a major role.
Quantitative Genetics
Quantitative genetics is the part of genetics that deals with the continuous trait, where the expression of various genes influences the phenotypes. Thus genes are expressed together to produce a trait with continuous variability. This is unlike the classical traits or qualitative traits, where each trait is controlled by the expression of a single or very few genes to produce a discontinuous variation.
Why is a chromosome with two centromeres (a
dicentric chromosome) unstable? Would a backup cen-
tromere not be a good thing for a chromosome, giving it
two chances to form a kinetochore and attach to microtu-
bules during mitosis? Would that not help to ensure that
the chromosome did not get left behind at mitosis?
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