What type of chromosomal rearrangement occurs If a single chromosome suffers two double-strand breaks followed by DNA repair that fuses the remaining broken ends (nonhomologous end-joining) if the intervening fragment rotates by 180°?

What type of chromosomal rearrangement occurs If a single chromosome suffers two double-strand breaks followed by DNA repair that fuses the remaining broken ends (nonhomologous end-joining) if the intervening fragment rotates by 180°?

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter8: The Structure, Replication, And Chromosomal Organization Of Dna

Section: Chapter Questions

Problem 25QP: Discuss the levels of chromosomal organization with reference to the following terms: a. nucleotide...

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Question

What type of chromosomal rearrangement occurs If a single chromosome suffers two double-strand breaks followed by DNA repair that fuses the remaining broken ends (nonhomologous end-joining) if the intervening fragment rotates by 180°
?

Expert Solution

Step 1

To explain:

To explain type of chromosomal rearrangement in the double stranded breaks in single chromosome followed by DNA repair that fuses the remaining broken ends if the fragment rotates by 180⁰.

Step 2

Answer:

The type of chromosomal rearrangement in the double stranded breaks in single chromosome followed by DNA repair that fuses the remaining broken ends if the fragment rotates by 180⁰ is called inversion.

Inversion is the reversal of the linear orientation of a chromosome segment and the order of its gene sequence, in relation to the arrangement in the rest of the chromosome.

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