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- 1. The frequency of a recessive disease is 9%. What is the frequency of the allele that causes s the disease? a) What is the frequency of the dominant allele? b) What is the frequency of the carriers (heterozygotes) of the disease?Explain the following1. A couple comes to a genetic councilor concerned about their chances of having a baby with cystic fibrosis disease. The husband had a sibling die of the disease. What are the chances that he is a carrier?8. Determine the genotype for each phenotype using the Information provided: SQUARE shape (S) Is dominant to ROUND shape (s) Square: Round:
- 4. STATEMENT: A woman who has blood type B positive has a daughter who is type 0 positive and a son who is type A negative. a) What is the genotype for the woman, daughter, son and man? Woman Daughter Son Man Genotype b) The woman and the man surprising are having a third child. What are the possible genotypes and phenotypes for their third child?1. Differentiate transplantation from explantation. 2. Differentiate autografting from heterografting to xenografting.14. Write the karyotype of a Turner syndrome. O A) 2n = 46 - 1 O B) 2n - 1 = 45 O C) 45, X O D) 46 - 1, X
- 5. A woman with type AB blood marries a man with type homozygous type B blood. What are the phenotype and genotype ratios of the offspring? 6. Hemophilia is a sex linked recessive trait. If a carrier woman marries a normal man. The couple gives birth to a boy. What are the chances that this child will have hemophilia? Make sure use XX or XY here) 7. The height of a certain plant is a result of polygenic inheritance involving two pairs of genes. Draw a Punnett square to show the result of a cross between a tall (AABB) plant and a short (aabbi. What is the phenotype ratio? 8. What is a mutation? 9. What is sickle cell anemia? 10. What is hemophilia? 11. What is a pedigree? 12. Draw a pedigree to represent the following. Shaded symbols should represent individuals with hemophilia: A man with hemophilia marries a normal woman. They have 3 children, two normal boys and a girl who is a carrier. The girl marries a normal man and they have two boys and two girls. One of the girls is a carrier…2. Describe the phenotype of individuals whe inherit two copies of the Hbs allele Sickle-Cell Disease.II. Write TRUE if the statement is correct and FALSE if otherwise. -7. A temale parent possessing an X-linked dominant mutation is considered a carrier and will not manifest clinical symptoms of the disorder. _8. Y-linked traits are passed from the father to son, without the occurrence of genetic recombination. 9. Somatic mosaicism results to abnormalities based on the amount and distribution of normal cells while gonadal mosaicism affects the germline tissues leading to a new dominant mutation. 10. A test cross is done to determine which allele is dominant and which is recessive.
- Additional problems (Chapter 4 (Extension of Mendelian Inheritance): 1. In rabbits, coloration of the fur depends on alleles of the gene c. From information given in the chapter, what phenotypes and proportions would be expected from the following crosses: a) CC X cc b) Cc x Cc c) Cc x Ccch d) cc x cc 2. From the information given in the chapter about the ABO blood types, what phenotypes and ratios are expected from the following matings: a) type AB x type O b) Type AB x type B individual whose mother is type O c) Type O x Type A individual whose father is type O d) Type Ox type O 3. A woman with type AB blood type gave birth to a baby with type B blood. Two different men claim to be the father. One has type A blood and the other type B blood. Can the genetic evidence decide in favor of either? 4. You have been studying a trait that seems to be present in every generation within a particular family. Further, you have observed that every affected offspring has at least affected parent…1. Give the genetic cause (chromosomal abnormality and genes affected), and major characteristics of the syndrome Miller Dieker syndrome Wolf-Hirschhorn syndrome Chronic myeloid leukemia/Philadelphia chromosome Acute promyelocytic leukemia Cri-du-chat6. A man with X-linked colorblindness marries a woman with no history of ibba colorblindness in her family. The daughter of this couple marries a normal man noitenmot and ended up hone daughter, and their daughter also marries a normal man. This mont blast couple has already had a child with color blindness. do sri ni novig A) What is the chance that next child will be color blind? B) What is the chance that this last couple will have an affected daughter? (d #50x²50 (