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1. Differentiate transplantation from explantation.
2. Differentiate autografting from heterografting to xenografting.
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- 3. A woman who is a carrier for hemophilia marries a normal man. a. What is the probability that their first child will be a hemophiliac girl? b. What is the probability that the child will be a girl who is a carrier for the disease? c. What is the probability that, if they have a son, he will be normal? d. What is the probability that they will have a son who is a carrier for the disease?4. STATEMENT: A woman who has blood type B positive has a daughter who is type 0 positive and a son who is type A negative. a) What is the genotype for the woman, daughter, son and man? Woman Daughter Son Man Genotype b) The woman and the man surprising are having a third child. What are the possible genotypes and phenotypes for their third child?5. Describe two ways to prevent getting an STI..?
- 8. The diagram below shows a pedigree of cystic fibrosis (CF), in which the black colour indicates the presence of CF. What is the probability that the individual labelled X is a carrier of CF? a) 100% b) 50% c) 25% d) 0%1. A patient has a mutated BRCA2 gene and a normal BRCA1 gene. Select the TWO answers that are correct. The patient has an increased risk of developing ovarian or breast cancer than a patient with normal BRCA1 and BRCA2 genes. The patient has a lesser risk of developing ovarian or breast cancer than a patient with normal BRCA1 and BRCA2 genes. The patient has a lesser risk of developing ovarian or breast cancer than a patient with a normal BRCA2 gene and a mutated BRCA1 gene. The patient has a greater risk of developing ovarian cancer and a lesser risk of developing breast cancer than a patient with normal BRCA1 and BRCA2 genes. The patient has a greater risk of developing breast cancer and a lesser risk of developing ovarian cancer than a patient with normal BRCA1 and BRCA2 genes.9. Explain what risk factors are involved in causing a "UTI"?
- 8. Determine the genotype for each phenotype using the Information provided: SQUARE shape (S) Is dominant to ROUND shape (s) Square: Round:3. D. A. B. C. 10. Familial hypercholesterolemia is the most common genetic cause of heart disease. It is caused by a dominant factor (C). The recessive factor (c) produces a protein that processes cholesterol normally and leads to a normal risk for heart disease. Answer the following questions about the inheritance of this disease. What is the phenotype of a woman whose genotype is Cc? What is the genotype of a man who has hypercholesterolemia but whose mother did not have the disease? If a man who is heterozygous for the disease marries a woman who is heterozygous for the disease, what is the chance that any child of theirs will inherit the disease? If a man who is homozygous dominant marries a woman who is homozygous recessive, what would you predict for the the genotypes and phenotypes of their children? If the first 2 children from the marriage described in D above have the disease, what is the chance that a third child would be normal? Explain your answer. 411. Provide the normal and mutated sequence of Leigh's diseases. 2. Provide the specific gene involved and the area where the mutation occurred.
- 3. Hemophilia is a sex linked trait that does not allow for blood clotting normally. It is a recessive genetic defect. In the royal family, the mother of the Prince is a carrier for hemophilia. (XHXh) while the father is normal. ( XHY) . What is the genotype of the Prince if he carries the bleeder’s disease? What is the probability that all the female princesses are normal? Use the Punnett square to show your solution.1. State the significance of compatibility test in transfusion medicine? 2. What is a major crossmatch? A minor crossmatch?2. What accounts for the oral and vaginal pain in patients with megalohlastic anaemia? 3. What are the determinants of the fate of a pluripotent stem cell? 4. Why would an adult who has been vegetarian for 2 years and has had menorrhagia for 5 years have microcytic red cells in a peripheral smear? 5. Which parts of the spinal cord are affected in patients with Sub Acute Combined degeneration? 6. Ovalocytes and hypersegmented neutrophil nuclei are more likely to be associated with what type ofanaemla. T. What is the ditference between megaloblasts and macrocytes? 8What are the distinguishing laboratory foatures between intravascular and extravascular haemolysis? maemia