1. Analyze Are any of Jerry's sibling homozygous for the sickle cell trait? Are any of Jerry's siblings heterozygous for sickle cell discase? 2. Analyze What genotype is Jerry's father? 3. Analyze What genotypes are Jerry's grandparents? 4. Infer What is the genotype of Jerry's mother? Explain.
1. Analyze Are any of Jerry's sibling homozygous for the sickle cell trait? Are any of Jerry's siblings heterozygous for sickle cell discase? 2. Analyze What genotype is Jerry's father? 3. Analyze What genotypes are Jerry's grandparents? 4. Infer What is the genotype of Jerry's mother? Explain.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Transcribed Image Text:5. Predict If Jerry marries a female who is heterozygous for the sickle cell trait,
what would be the possible genotypes and phenotypes of their children? Use a
Punnett square to find your answer. Fill in the top boxes with Jerry's genotype;
fill in the side boxes with Jerry's wife's genotype. Fill in the square with all
possible genotypes for their children.
(Jerry)
(Wife)
Transcribed Image Text:BACKGROUND
Sickle cell disease is caused by a change in the gene for hemoglobin, which is the
oxygen-carrying protein in red blood cells. Individuals who are homozygous for
the sickle cell trait often cannot endure exercise. Individuals who are heterozygous
for the trait can have sickle cell attacks under extreme conditions. Normal
individuals (Hb Hb) have only normal hemoglobin. Homozygous sickle cell
individuals (Hb Hb') have only sickle cell hemoglobin. Heterozygous individuals
(Hbs Hb) have both normal hemoglobin and sickle cell hemoglobin.
Jerry Smith collapsed while running a race for his track team. A doctor said that
he had a sickle cell attack. Genetic tests were run on several family members. The
test results are shown below. An X indicates that form of hemoglobin in red blood
cells.
PROBLEM
How can you determine the genotypes of people in a family?
TABLE 1. FAMILY PHENOTYPES
Normal Hemoglobin
Subject
Jerry Smith
Jerry's brother
Jerry's younger sister
Jerry's youngest sister
Jerry's father
Jerry's grandfather
Jerry's grandmother
MATERIALS
• paper
• pencil
Houghton Mifflin Harcourt Publishing Company
Holt McDougal Biology
Chapter Investigation
Name
Codominance continued
PROCESS SKILLS
• Inferring
• Predicting
X
X
X
X
X
X
X
3
Period
Sickle Cell Hemoglobin
2. Analyze What genotype is Jerry's father?
X
Extending Mendelian Genetics
Section 2: Complex Patterns of Inheritance
Date
3. Analyze What genotypes are Jerry's grandparents?
X
PROCEDURE
1. Use the background information and the genetic test results to answer
questions 1-4.
X
2. Use the background information and a Punnett square to help you answer
question 5.
4. Infer What is the genotype of Jerry's mother? Explain.
ANALYZE AND CONCLUDE
1. Analyze Are any of Jerry's sibling homozygous for the sickle cell trait? Are
any of Jerry's siblings heterozygous for sickle cell discase?
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