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1. Analyze Are any of Jerry's sibling homozygous for the sickle cell trait? Are any of Jerry's siblings heterozygous for sickle cell discase? 2. Analyze What genotype is Jerry's father? 3. Analyze What genotypes are Jerry's grandparents? 4. Infer What is the genotype of Jerry's mother? Explain.

1. Analyze Are any of Jerry's sibling homozygous for the sickle cell trait? Are any of Jerry's siblings heterozygous for sickle cell discase? 2. Analyze What genotype is Jerry's father? 3. Analyze What genotypes are Jerry's grandparents? 4. Infer What is the genotype of Jerry's mother? Explain.

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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5. Predict If Jerry marries a female who is heterozygous for the sickle cell trait, what would be the possible genotypes and phenotypes of their children? Use a Punnett square to find your answer. Fill in the top boxes with Jerry's genotype; fill in the side boxes with Jerry's wife's genotype. Fill in the square with all possible genotypes for their children. (Jerry) (Wife)
Transcribed Image Text:5. Predict If Jerry marries a female who is heterozygous for the sickle cell trait, what would be the possible genotypes and phenotypes of their children? Use a Punnett square to find your answer. Fill in the top boxes with Jerry's genotype; fill in the side boxes with Jerry's wife's genotype. Fill in the square with all possible genotypes for their children. (Jerry) (Wife)
BACKGROUND Sickle cell disease is caused by a change in the gene for hemoglobin, which is the oxygen-carrying protein in red blood cells. Individuals who are homozygous for the sickle cell trait often cannot endure exercise. Individuals who are heterozygous for the trait can have sickle cell attacks under extreme conditions. Normal individuals (Hb Hb) have only normal hemoglobin. Homozygous sickle cell individuals (Hb Hb') have only sickle cell hemoglobin. Heterozygous individuals (Hbs Hb) have both normal hemoglobin and sickle cell hemoglobin. Jerry Smith collapsed while running a race for his track team. A doctor said that he had a sickle cell attack. Genetic tests were run on several family members. The test results are shown below. An X indicates that form of hemoglobin in red blood cells. PROBLEM How can you determine the genotypes of people in a family? TABLE 1. FAMILY PHENOTYPES Normal Hemoglobin Subject Jerry Smith Jerry's brother Jerry's younger sister Jerry's youngest sister Jerry's father Jerry's grandfather Jerry's grandmother MATERIALS • paper • pencil Houghton Mifflin Harcourt Publishing Company Holt McDougal Biology Chapter Investigation Name Codominance continued PROCESS SKILLS • Inferring • Predicting X X X X X X X 3 Period Sickle Cell Hemoglobin 2. Analyze What genotype is Jerry's father? X Extending Mendelian Genetics Section 2: Complex Patterns of Inheritance Date 3. Analyze What genotypes are Jerry's grandparents? X PROCEDURE 1. Use the background information and the genetic test results to answer questions 1-4. X 2. Use the background information and a Punnett square to help you answer question 5. 4. Infer What is the genotype of Jerry's mother? Explain. ANALYZE AND CONCLUDE 1. Analyze Are any of Jerry's sibling homozygous for the sickle cell trait? Are any of Jerry's siblings heterozygous for sickle cell discase?
Transcribed Image Text:BACKGROUND Sickle cell disease is caused by a change in the gene for hemoglobin, which is the oxygen-carrying protein in red blood cells. Individuals who are homozygous for the sickle cell trait often cannot endure exercise. Individuals who are heterozygous for the trait can have sickle cell attacks under extreme conditions. Normal individuals (Hb Hb) have only normal hemoglobin. Homozygous sickle cell individuals (Hb Hb') have only sickle cell hemoglobin. Heterozygous individuals (Hbs Hb) have both normal hemoglobin and sickle cell hemoglobin. Jerry Smith collapsed while running a race for his track team. A doctor said that he had a sickle cell attack. Genetic tests were run on several family members. The test results are shown below. An X indicates that form of hemoglobin in red blood cells. PROBLEM How can you determine the genotypes of people in a family? TABLE 1. FAMILY PHENOTYPES Normal Hemoglobin Subject Jerry Smith Jerry's brother Jerry's younger sister Jerry's youngest sister Jerry's father Jerry's grandfather Jerry's grandmother MATERIALS • paper • pencil Houghton Mifflin Harcourt Publishing Company Holt McDougal Biology Chapter Investigation Name Codominance continued PROCESS SKILLS • Inferring • Predicting X X X X X X X 3 Period Sickle Cell Hemoglobin 2. Analyze What genotype is Jerry's father? X Extending Mendelian Genetics Section 2: Complex Patterns of Inheritance Date 3. Analyze What genotypes are Jerry's grandparents? X PROCEDURE 1. Use the background information and the genetic test results to answer questions 1-4. X 2. Use the background information and a Punnett square to help you answer question 5. 4. Infer What is the genotype of Jerry's mother? Explain. ANALYZE AND CONCLUDE 1. Analyze Are any of Jerry's sibling homozygous for the sickle cell trait? Are any of Jerry's siblings heterozygous for sickle cell discase?
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