D. A. B. 10. C. Familial hypercholesterolemia is the most common genetic cause of heart disease. It is caused by a dominant factor (C). The recessive factor (c) produces a protein that processes cholesterol normally and leads to a normal risk for heart disease. Answer the following questions about the inheritance of this disease. What is the phenotype of a woman whose genotype is Cc? What is the genotype of a man who has hypercholesterolemia but whose mother did not have the disease? If a man who is heterozygous for the disease marries a woman who is heterozygous for the disease, what is the chance that any child of theirs will inherit the disease? If a man who is homozygous dominant marries a woman who is homozygous recessive, what would you predict for the the genotypes and phenotypes of their children? If the first 2 children from the marriage described in D above have the disease, what is the chance that a third child would be normal? Explain your answer.

Explain the concept of carriers and describe several types.

explain pleiotropy in sickle cell disease.

1. Identify the two most common types of genetic disorders called hemophilia. Explain how each of the two types of hemophilia results in impaired hemostasis.  2. Explain how the endocrine system contributes to the hemostasis of blood oxygen levels.