1 Infected bacterium Phage integration of spacer Cas protein Spacer Phage DNA Phage DNA is cut into fragments. cas genes CRISPR array 2 Surviving bacterium Transcription CRISPR RNA RNA processing 3 Immunity crRNAS Phage Cas-crRNA 区、 complex Invading viral DNA is inactivated by Cas-crRNA complex. Cas-crRNA complex FIGURE 13.11 CRISPR Defense System Agalnst Phage Infection

Biology: The Unity and Diversity of Life (MindTap Course List)
14th Edition
ISBN:9781305073951
Author:Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr
Publisher:Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr
Chapter15: Studying And Manipulating Genomes
Section: Chapter Questions
Problem 12SQ: Which of the following can be used to carry foreign DNA into host cells? Choose all correct answers....
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How does the CRISPR system target nucleic acid of an invading phage for destruction?

1 Infected bacterium
Phage
integration
of spacer
Cas protein
Spacer
Phage DNA
Phage DNA
is cut into
fragments.
cas genes
CRISPR array
2 Surviving bacterium
Transcription
CRISPR RNA
RNA processing
3 Immunity
crRNAS
Phage
Cas-crRNA
区、
complex
Invading viral
DNA is inactivated
by Cas-crRNA
complex.
Cas-crRNA
complex
FIGURE 13.11 CRISPR Defense System Agalnst Phage Infection
Transcribed Image Text:1 Infected bacterium Phage integration of spacer Cas protein Spacer Phage DNA Phage DNA is cut into fragments. cas genes CRISPR array 2 Surviving bacterium Transcription CRISPR RNA RNA processing 3 Immunity crRNAS Phage Cas-crRNA 区、 complex Invading viral DNA is inactivated by Cas-crRNA complex. Cas-crRNA complex FIGURE 13.11 CRISPR Defense System Agalnst Phage Infection
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