Myasthenia Syndrome Research Paper

This disease affects the nerve cells by enabling them to send electric impulses to the muscles which ultimately makes the muscle wither away and stop working. The nerves targeted are actually

Guillain-Barre Syndrome (GBS) is a rare autoimmune disease. This is where an individual’s own immune system attacks and destroy healthy body tissue. The exact cause of this syndrome is unknown. However, once triggered the immune system begins to attack the myelin sheath in the brain, particularly, your peripheral nervous system (PNS). The PNS connects the brain and spinal cord (central nervous system – CNS) to the rest of the body. The myelin sheath main function is to ensure fast propagation of nerve impulses. When damaged it can often result in muscle weakness or paralysis.

Myasthenia Gravis (MG) is a chronic autoimmune disorder of the neuromuscular system part of the body. Chronic means persisting for a long time or constantly recurring. Autoimmune disorder is the confusion of the body’s immune system. The immune system form antibodies that mistakenly identify healthy tissue as foreign and then, the antibodies will attack and/or destroy healthy body tissue. Neuromuscular is the nervous system relationship with the muscles bring about body movement.

Since this condition may have devastating complications and can affect quality of life, it is important to become educated about its symptoms, diagnosis, and treatment.

One type of drug class are anticholinesterase, which inhibits acetylcholine in order to increase the levels of Ach in the body to bind to functional receptors to increase the amount of synapses. Corticosteroids and immunosuppresants are other drugs that can be used to suppress the immune system’s attack on the motor end plates. To stop developing tumors on their thymus, patients might opt to have their thymus removed by a procedure called a thymectomy. Another procedure that can be done is a plasmapheresis, which reduces the number of antibodies in the blood so there are more open receptors for Ach to bind to. However, it is important to know that treatment varies from patient to patient and no patient is the same with this

Myasthenia Granis is an autoimmune disorder affecting the myoneural function, it is characterized by varying degrees of weakness of the voluntary muscles, often it affects more men than women. It occurs when antibodies at the ACH sites impair transmission of the impulses across the myoneural function. Manifestations such as diplopia, ptosis and facial weaknesses are common (Hinkle &Cheever, 2014).

Lambert-Eaton myasthenic syndrome, also known as Eaton Lambert syndrome, is an autoimmune disease that is characterized by the onset of severe muscle weakness. The muscle weakness involved with Lambert-Eaton myasthenic syndrome (LEMS) typically occurs in the pelvis and thigh muscles. Approximately 60 percent of LEMS cases are associated with a small cell lung cancer (SCLC), and the onset of LEMS symptoms often precedes the detection of the cancer (Gozzard). Patients who have LEMS that also have cancer tend to have a history of smoking and are usually older adults. LEMS occurs often in men with tumors in their chests, especially lung cancer. Individuals without cancer can develop LEMS at any age. However, LEMS is rarely seen in children and this disease is not hereditary. This disease is also more common in men than in women and the progression depends on whether it occurs with cancer.

Myasthenia Gravis is an autoimmune disorder in which antibodies destroy neuromuscular connections which leads to problems with the nerves that control muscles. The disease is characterized by weakness and fatigability of skeletal muscles. The muscles mainly affected are that of the eye, mouth, throat and limbs. The key concept underlying the disease is the decrease in the number of available acetylcholine receptors at neuromuscular junctions due to an antibody mediated auto-immune attack. The disease was first documented by the great physiologist Thomas Willis about 300 years ago (1). More importantly, extensive research and studying has led to greater understanding of the disease during the

Myasthenia Gravis is an autoimmune disease of the neuromuscular junction which usually causes muscle weakness and other problems. Some of the people who have Myasthenia Gravis experience respiratory failures. It’s very crucial that these patients stay away from interventions that might worsen the disease process. In 2014 a 62 year old woman with a history of metastatic thymic carcinoma and myasthenia gravis came to the emergency room in Houston, Texas. For two days this lady had been experiencing weakness, difficulty swallowing, and shortness of breath. They admitted her into the intensive care unit because she had the symptoms of a myasthenia crisis. That evening they ran a test and there was a substantial decrease in the patient’s vital capacity. The patient wouldn’t agree to be intubated or ventilated. On the third day in the ICU the patient was granted a trial of non-invasive ventilation, but this did not improve her condition. So finally she agreed to be intubated

Myasthenia gravis is an immune-mediated disorder by fatigue of skeletal muscles. This typically involves extrinsic ocular or bulbar areas. This disease is usually found in older people but most people do not recognize it and it is rare. It is often confused with cerebrovascular disease. This disease is a post-synaptic neuromuscular junction disorder. There is always fatigue present in this disease. Patients have to take different test such as, itive nerve stimulation and antibody serology.

At an almost ironically small 1500 grams (3.3 pounds) the human brain is considered the “command center” of the human intelligence. With the help of the branching nerves, the brain has ability to interpret senses, to achieve the movement of the body and act as regulator of all behaviors; and that’s just a small fraction of the nervous systems responsibilities. As the Nervous System, the brain and nerves work in close association with the rest of our body systems to generate the hundreds of thousands of basic steps needed for life. In this multifaceted body system, any seemingly trivial error can lead to catastrophic alteration to the machine that is the human body. We are constantly achieving understanding of the mechanisms of diseases and syndromes and somehow there is still, simultaneously, an abundance of new pathologies that science has yet begun to understand. One such disease that affects the nervous system specifically is Schwannomatosis. In this paper, we will discuss the symptoms, platforms of the disease, complications, some treatment options and outcomes.

We learned through research that myasthenia gravis and myotonic muscular dystrophy are two common forms of muscular disorders. Myasthenia gravis is a neuromuscular disorder that usually occurs in the arms, head and chest (2). Its symptoms include limb weakness, drooping eyelids, impaired vision, difficulty chewing and swallowing, slurred speech, difficulty breathing and abnormality of the thymus gland (3). Myotonic muscular dystrophy is one of many forms of muscular dystrophy that is characterized by muscle wasting and myotonia or the inability to relax muscles (4). Its symptoms include, but are not limited to drooping eyelids, cataracts,

LEMS can be either an autoimmune or a paraneoplastic condition. Antibodies are directed against the presynaptic P/Q voltage gated calcium channels (VGCC), resulting in reduced release from of acetylcholine.

The main symptom of these disorders is tumors that form on the ends of nerves throughout the body. NF 1 is most commonly

After all three days of research, I had now gathered all my information and answered almost all my questions. From Myasthenia.org I figured out that the most common form of MG is a chronic autoimmune neuromuscular disorder. The symptoms vary but the main symptom is muscle weakness in the eyes, neck, and limbs. With severe cases of MG (such as a class 4 or 5 MG) the weakness in the mouth or respiratory may be more prominent. This muscle weakness is caused by blocked receptor sites. These receptor sites help involuntary muscles, when they are blocked it causes the weakness. Some cases of MG can have as much as 80% reduction of activeness in some receptor sites. Most symptoms are not immediately recognized as MG but the initial set off of