Taking a Look at Myasthenia Gravis

Limb-girdle muscular dystrophy is another disease that causes weakness and wasting of the muscles. Limb-girdle muscular dystrophy (LGMD) is an extremely rare disease that specifically affects the bony structures that surround the hip and shoulders. The bony structures that surround

Duchenne muscular Dystrophy (DMD) is the most common out of nine types of muscular dystrophy. This genetic disorder causes progressive muscular weakness, and deterioration due to the lack of a protein called Dystrophin. This protein keeps the muscles in tack, so when it's missing, the muscles slowly break down. (MDA, 2015)

The most common features of Neuromyotonia is muscle stiffness, muscles contracting, twitching muscles (myokymia), and weakened reflexes. These symptoms can be designated to a particular area, usually the face and hands or throughout the body. Stiffness is mostly featured in the limbs and trunk muscles. Observable symptoms include abnormal movements, pains and cramps. Behavioral changes include disruptive sleep, excessive sweating, although these types of symptoms are uncommon. Symptoms can occur during sleep and when under anesthesia. Muscle fiber excessive activity can lead to muscle weakness or increase size of muscle cells known as hypertrophy (David, Firth, Cox 515). Being diagnose with Neuromyonia ranges from a wide age range fifthteen to sixty, most people experience signs before their forties (Maddison 2119).

The symptoms may seem obvious for muscular dystrophy. When muscles degenerate, they cannot be used at the fullest potential. The earliest symptom may be delayed walking in children (Bushby et al., 2009). A reduction in size and strength of muscle is another sign that muscles could be degenerating. The variations of muscular dystrophy disease target different and several muscles. Having trouble using a group of muscles may be a sign of muscular dystrophy disease. Some may have trouble standing up, and some people may fall frequently also (How is muscular, n.d.). If the patient has weak respiratory muscles, they may have trouble breathing due to a lack of airflow (Makker, H., M., & P, 2012).

Myasthenia gravis may affect any voluntary muscles. They may affect muscles that control the eyelid movement, facial expression and swallowing. The most symptoms of myasthenia gravis that can be noticed are the weakness of the eye muscle that causes double vision. Some symptoms of myasthenia gravis may include unstable walk, arm weakness, weakness in hands, fingers, legs and neck, change in facial expression, having a hard time swallowing, shortness of breath, and having problems with

Myasthenia Gravis (MG) is a chronic autoimmune disorder of the neuromuscular system part of the body. Chronic means persisting for a long time or constantly recurring. Autoimmune disorder is the confusion of the body’s immune system. The immune system form antibodies that mistakenly identify healthy tissue as foreign and then, the antibodies will attack and/or destroy healthy body tissue. Neuromuscular is the nervous system relationship with the muscles bring about body movement.

Myotonic Dystrophy is the most common form of muscular dystrophy. It is a chronic, multi-system disorder that is characterized by progressive muscle wasting and weakness. Symptoms include; myotonia (prolonged muscle contractions), the inability to relax certain muscles after use, slurred speech, temporary locking of jaw, cataracts, abnormalities of the electrical signals that control the heartbeat, and early balding and infertility in men. There are two major types of myotonic dystrophy, type 1 and type 2. Many of the symptoms are overlapping, the only differences are type 1 is generally more severe than type 2 and type 1 affects the lower legs, hands, neck and face. Whereas, type 2 affects the neck, shoulders, elbows, and hips. Myotonic dystrophy

Damage to the neuromuscular junctions is due to an autoimmune disease called myasthenia graves. The motor end plates, which are located on skeletal muscles, are affected because there is a decrease in the amount of Ach receptors located on the motor end plate, which is connected to the neuromuscular junction. The decrease is due to the unnecessary production of antibodies, which bind to the motor end plate. This prevents Ach from binding to the receptors to carry out a synapse between the skeletal muscle and a neuron, leading to a stop or weakening of muscle contraction. The decrease in the amounts of synapses cause the skeletal muscle to lose function, become weaker, and tire more easily.

Emery-Dreifuss Muscular Dystrophy (EDMD) - This is 1/9 types of muscular dystrophy, these diseases mainly affect your voluntary muscles. It’s named after Alan Emery and Fritz Dreifuss, physicians who first described this disease in the 1960s. EDMD is caused by gene mutations that cause the produce of proteins in the nuclear membrane of each muscle cell. Also it can be inherited in a number of ways, but each inheritance pattern usually has the same symptoms. EDMD usually shows itself by the age of 10 and it’s described as the wasting and weakness of muscles making up your shoulders, upper arms, and calf muscles of legs. Another major EDMD aspect is appearance of contractures (stiff joints) in the elbows, neck, and heels early in the disease’s

Muscular dystrophy (MD) is a genetic disorder caused by incorrect or missing genetic information that leads to the gradual weakening of the muscle cells. Various causes lead to weak and deteriorating muscles depending on the type of muscular dystrophy the patient was affected by. However, there are many causes for muscular dystrophy due to the fact that there are thirty forms of muscular dystrophy, which are categorized under several categories. All are ultimately caused by autosomal recessive, autosomal dominant, sex-linked, and random mutations in very rare cases.

Muscular Dystrophy (MD) is a disease that can be defined as a group of genetic traits that includes deteriorating by the voluntary muscular and/or skeletal movements. Other organs such as the heart are another example of an involuntary muscle that can easily be affected by the disease. Muscular Dystrophy can effect anyone - child or infant, and even middle age to older adults. The overall severity of the disease depends on when it decides to show up. Some factors are simply the age of the individual, the current condition or strength of their muscles, how fast the disease progresses, and as well genes. Most do are not fully aware of the severity of the disease, nor do they know that there are nine different types out there. Some types of Muscular Dystrophy affect males.

Muscular dystrophy is a hereditary condition marked by progressive weakening and wasting of the muscles. The main sign of muscular dystrophy is progressive muscle weakness. Specific symptoms start at different ages and in different muscle groups, depending on the type of muscular dystrophy. This disease can appear in infancy up to middle age or older. There are 9 major types of muscular dystrophy. Myotonic, Duchenne, Becker, limb-girdle, facioscapulohumeral, congenital, oculopharyngeal, distal, and emery-dreifuss. The diagnostic of muscular dystrophy can be found through a physical exam, family medical history, and tests. Furthermore, those include muscle biopsies, DNA testing, nerve conduction tests, and blood enzyme tests. Muscular dystrophy

Now different types of MD affect different types of muscles. For example, Duchenne and Becker (DBMD) mainly affects the upper arms and upper legs first, whereas Myotonic Muscular Dystrophy (MMD) usually affects the Face, neck, arms, hands, hips, and lower legs first. The muscles in our body help us in our everyday routine, ranging from being able to lift heavy object, to being able to do something as simple as walking. Since MD targets the muscles it becomes difficult to near impossible to accomplish these tasks. It is common for people who have had MD for 5 years or more to be stricken to a wheelchair because the muscles in the legs have weakened to the point of non-existence.

There are over 30 types of Muscular Dystrophy. I am only going to discuss a few of the most common kinds. The first one I am going to discuss is the most common type and the most severe type of Muscular Dystrophy, Duchene Muscular Dystrophy (DMD). This type of MD affects mostly boys between the ages of 3 and 5 and accounts for over 50% of all cases. This deficiency is caused by a lack of dystrophin, a protein that helps reinforce muscle fibers and shield them from injury. This type of disease progresses very fast and by the age of 12 most can’t walk. Some of the signs you might see in an individual with this disease are falling down, trouble getting up from lying down or sitting position, and a swayed gate. As the disease further progresses they will need to be placed on a respirator which can lead to complications and by their early 20’s most pass away (5).

This diagnosis (learning what is wrong) is made by the obvious symptoms (problems) of contraction of multiple muscles in the body and the usual rapid response to treatment. Because of multiple