Essentials of Genetics (9th Edition) - Standalone book
9th Edition
ISBN: 9780134047799
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Chapter 4, Problem 27PDQ
Two mothers give birth to sons at the same time at a busy urban hospital. The son of mother 1 is afflicted with hemophilia, a disease caused by an X-linked recessive allele. Neither parent has the disease. Mother 2 has a normal son, despite the fact that the father has hemophilia. Several years later, couple 1 sues the hospital, claiming that these two newborns were swapped in the nursery following their birth. As a genetic counselor, you are called to testify. What information can you provide the jury concerning the allegation?
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In man, muscular dystrophy is a condition in which the muscles waste away during early life and may result in a shorter life expectancy. It is due to a sex-linked, recessive gene. A certain couple has five children – three boys (ages 1yr, 3yrs, and 10yrs old) and two girls (ages 5yrs and 7yrs old). The oldest boy shows the symptoms of this disease. You are their family physician and they come to you for advice. What would you tell them about the chances of their other children developing the disease?
A woman knows that her mother is a carrier of Kartagener’s syndrome (an autosomal recessive disorder). The woman does not know if either she or her husband are carriers. The couple wants to have a child, but is worried about whether or not they could have a child with Kartagener’s syndrome. Should the couple seek the advice of a genetic counselor? In other words, is there a chance they could have an affected child? If there is a chance, please make sure your answer includes the specific parental genotypes necessary to make this possible.
You are a genetic counselor. How would you advise a couple who wants to know their chances of having a baby with Duchenne-muscular dystrophy. Hannah is not a carrier, but her husband Barry has a brother, James, who died from the disease. Duchenne-muscular dystrophy is an x-linked condition, the allele responsible is recessive and people who have the disease die in childhood.
a)What are Hannah’s and Barry’s chances of having a baby with Duchenne-muscular dystrophy?
b)What are the chances of Barry’s sister having a baby with the disease?
Chapter 4 Solutions
Essentials of Genetics (9th Edition) - Standalone book
Ch. 4 - CASE STUDY | But he isn't deaf Researching their...Ch. 4 -
CASE STUDY | But he isn’t deaf
Researching...Ch. 4 - CASE STUDY | But he isn't deaf Researching their...Ch. 4 - HOW DO WE KNOW? In this chapter, we focused on...Ch. 4 - Review the Chapter Concepts list on page 53. These...Ch. 4 - In Shorthorn cattle, coat color may be red, white,...Ch. 4 -
4. With regard to the ABO blood types in humans,...Ch. 4 - In foxes, two alleles of a single gene, P and p,...Ch. 4 - Three gene pairs located on separate autosomes...Ch. 4 - As in the plants of Problem 6, color may be red,...
Ch. 4 -
8. The following genotypes of two independently...Ch. 4 - Given the inheritance pattern of coat color in...Ch. 4 - A husband and wife have normal vision, although...Ch. 4 - In humans, the ABO blood type is under the control...Ch. 4 - In goals, development of the beard is due to a...Ch. 4 -
13. In cats, orange coal color is determined by...Ch. 4 - In Drosophila, an X-linked recessive mutation,...Ch. 4 - Another recessive mutation in Drosophila, ebony...Ch. 4 - While vermilion is X-linked in Drosophila and...Ch. 4 - In pigs, coat color may be sandy, red, or white. A...Ch. 4 - A geneticist from an alien planet that prohibits...Ch. 4 - In another cross, the frog geneticist from Problem...Ch. 4 - In cattle, coats may be solid white, solid black,...Ch. 4 - Consider the following three pedigrees, all...Ch. 4 - Labrador retrievers may be black, brown, or golden...Ch. 4 - Three autosomal recessive mutations in Drosophila,...Ch. 4 -
24. Horses can be cremello (a light cream...Ch. 4 - Pigment in the mouse is produced only when the C...Ch. 4 - Five human matings numbered 1–5 are shown in the...Ch. 4 - Two mothers give birth to sons at the same time at...Ch. 4 - In Dexter and Kerry cattle, animals may be polled...Ch. 4 - What genetic criteria distinguish a case of...Ch. 4 -
30. The specification of the anterior-posterior...Ch. 4 - The maternal-effect mutation bicoid(bcd)is...Ch. 4 -
32. Students taking a genetics exam were...Ch. 4 - In four o'clock plants, many flower colors are...Ch. 4 - Prob. 34PDQ
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