(a)
Interpretation:
The structure of the conjugate base of warfarin is to be drawn.
Concept introduction:
Warfarin is used as one of the anticoagulant agents. In the market, it is sold as Coumadin brand. It is not advisable to use it in pregnancy. It has adverse side effects like bleeding, purple toe syndrome, calcification. The X-ray studies confirm that it exists as a cyclic hemiketal tautomeric form.
(b)
Interpretation:
The unusual low
Concept introduction:
Warfarin is used as one of the anticoagulant agents. In the market, it is sold as Coumadin brand. It is not advisable to use it in pregnancy. It has adverse side effects like bleeding, purple toe syndrome, calcification. The X-ray studies confirm that it exists as a cyclic hemiketal tautomeric form.
(c)
Interpretation:
Whether at physiological
Concept introduction:
Warfarin is used as one of the anticoagulant agents. In the market, it is sold as Coumadin brand. It is not advisable to use it in pregnancy. It has adverse side effects like bleeding, purple toe syndrome, calcification. The X-ray studies confirm that it exists as a cyclic hemiketal tautomeric form.
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Organic Chemistry
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- Give reasons for the following :(i) Phenol is more acidic than methanol.(ii) The C—O—H bond angle in alcohols is slightly less than the tetrahedral angle (190°28′).(iii) (CH3)3C—O—CH3 on reaction with HI gives (CH3)3C—I and CH3—OH as the main products and not (CH3)3C—OH and CH3—I.arrow_forwardDraw the structure of the predominant form of CF3CH2OH (pK a = 12.4) at pH = 6.arrow_forwardно HO но он The pK, of ascorbic acid (vitamin C) is 4.17, showing that it is slightly more acidic than acetic acid (CH3CO0H, pKa 4.74). (a) Show the fou r different conjugate bases that would be formed by deprotonation of the four different OH groups in ascorbic acid. (b) Compare the stabilities of these four conjugate bases, and predict which OH group of ascorbic acid is the most acidic. (c) Compare the most stable conjugate base of ascorbic acid with the conjugate base of acetic acid, and suggest why these two compounds have similar acidities, even though ascorbic acid lacks the carboxylic acid (COOH) group.arrow_forward
- (b) A compound with the molecular formula C4H9CI has four structural isomers. Write the structural formulas for all the four isomers. (c) Arrange the following compounds in order of increasing acidity, and explain the reasons forarrow_forward(a) Rank the following compounds in order of increasing acidity. (b) Which compound forms the strongest conjugate base?arrow_forwardWhen the conjugate acid of aniline, C6H5NH3+, reacts with the acetate ion, the following reaction takes place: C6H5NH3+(aq)+CH3COO(aq)C6H5NH2(aq)+CH3COOH(aq) If Kafor C6H5NH3+ is 1.35105 and Kafor CH3COOH is 1.86105 , what is K for the reaction?arrow_forward
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